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516705 o-Phenanthroline - CAS 5144-89-8 - Calbiochem

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells.

o-Phenanthroline - CAS 5144-89-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,10-Phenanthroline Monohydrate

Primary Target: Metalloprotease inhibitor
516705
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
5144-89-8C₁₂H₈N₂ · H₂O

Products

Katalogové čísloBalení ks/bal.
516705-500MG Hliníkový sud 500 mg
Description
OverviewA metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a metalloprotease inhibitor. Inhibits glioma invasion in vitro.
Catalogue Number516705
Brand Family Calbiochem®
Synonyms1,10-Phenanthroline Monohydrate
References
ReferencesStix, B., et al. 2001. Am. J. Pathol. 159, 561.
Bolzan, A.D., et al. 2000. Mutat. Res. 447, 221.
Wang, Y., et al. 1999. J. Biol. Chem. 274, 33043.
Harayama, T., et al. 1999. Jpn. J. Can. Res. 90, 942.
Krane, S.M., et al. 1996. J. Biol. Chem. 271, 28509.
Uhm, J.H., et al. 1996. Clin. Exp. Metastasis 14, 421.
Product Information
CAS number5144-89-8
ATP CompetitiveN
FormWhite to cream solid
Hill FormulaC₁₂H₈N₂ · H₂O
Chemical formulaC₁₂H₈N₂ · H₂O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMetalloprotease inhibitor
Purity≥99% by titration
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSSF8437000
Safety Information
R PhraseR: 25-50/53

Toxic if swallowed.
Very toxic to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
S PhraseS: 45-60-61-37

In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
This material and its container must be disposed of as hazardous waste.
Avoid release to the environment. Refer to special instructions/safety data sheet.
Wear suitable gloves.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +15°C to +30°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 3 months at 4°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
516705-500MG 04055977198287

Documentation

o-Phenanthroline - CAS 5144-89-8 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

o-Phenanthroline - CAS 5144-89-8 - Calbiochem Certificates of Analysis

TitleLot Number
516705

References

Přehled odkazů
Stix, B., et al. 2001. Am. J. Pathol. 159, 561.
Bolzan, A.D., et al. 2000. Mutat. Res. 447, 221.
Wang, Y., et al. 1999. J. Biol. Chem. 274, 33043.
Harayama, T., et al. 1999. Jpn. J. Can. Res. 90, 942.
Krane, S.M., et al. 1996. J. Biol. Chem. 271, 28509.
Uhm, J.H., et al. 1996. Clin. Exp. Metastasis 14, 421.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-August-2018 JSW
Synonyms1,10-Phenanthroline Monohydrate
DescriptionA metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a general matrix metalloproteinase inhibitor. Forms a red chelate with Fe2+ that absorbs maximally at 510 nm. Can be used as a photometric reagent for iron.
FormWhite to cream solid
Intert gas (Yes/No) Packaged under inert gas
CAS number5144-89-8
RTECSSF8437000
Chemical formulaC₁₂H₈N₂ · H₂O
Structure formulaStructure formula
Purity≥99% by titration
SolubilityDMSO (100 mg/ml), ethanol (25 mg/ml), or H₂O (3 mg/ml)
Storage Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 3 months at 4°C.
Toxicity Toxic
Merck USA index14, 7214
ReferencesStix, B., et al. 2001. Am. J. Pathol. 159, 561.
Bolzan, A.D., et al. 2000. Mutat. Res. 447, 221.
Wang, Y., et al. 1999. J. Biol. Chem. 274, 33043.
Harayama, T., et al. 1999. Jpn. J. Can. Res. 90, 942.
Krane, S.M., et al. 1996. J. Biol. Chem. 271, 28509.
Uhm, J.H., et al. 1996. Clin. Exp. Metastasis 14, 421.