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14-654M eEF-2K Protein, active, 250 µg

Active, N-terminal GST-tagged, recombinant, human eEF-2K, amino acids 2-end, for use in Kinase Assays.

14-654M
250 µg  Also available in 10 μg size (cat#14-654) and in bulk (cat#14-654-K).
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Replacement Information
Description
Catalogue Number14-654M
Brand Family Upstate
Trade Name
  • Upstate
DescriptioneEF-2K Protein, active, 250 µg
OverviewN-terminal GST-tagged, recombinant, human eEF-2K, amino acids 2-end
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal GST-tagged, recombinant, human eEF-2K, amino acids 2-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed in E. coli cells
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Gene Symbol
  • EEF2K
  • MGC45041
  • HSU93850
  • eEF-2K
Protein TargeteEF-2K
Purification MethodGlutathione-agarose
Target Sub-FamilyMisc
UniProt Number
UniProt SummaryFUNCTION: SwissProt: O00418 # Phosphorylates eukaryotic elongation factor-2. Binds calmodulin (By similarity).
SIZE: 725 amino acids; 82172 Da
SUBUNIT: Monomer or homodimer (Potential).
SIMILARITY: SwissProt: O00418 ## Contains 1 alpha-type protein kinase domain.
Molecular Weight108.5kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of EF2tide (Catalog# 12-560)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditionsstable 6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-654) and in bulk (cat#14-654-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
14-654M 04053252924606

Documentation