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662041 U-73343 - CAS 142878-12-4 - Calbiochem

A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

U-73343 - CAS 142878-12-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione

Primary Target: Negative control of U-73122 in the inhibition of phospholipase C
662041
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
142878-12-4C₂₉H₄₂N₂O₃

Products

Katalogové čísloBalení ks/bal.
662041-5MG Plastová ampulka 5 mg
Description
OverviewA cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
Catalogue Number662041
Brand Family Calbiochem®
Synonyms1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione
References
ReferencesTatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther. 255, 756.
Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther. 253, 688.
Product Information
CAS number142878-12-4
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₂₉H₄₂N₂O₃
Chemical formulaC₂₉H₄₂N₂O₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNegative control of U-73122 in the inhibition of phospholipase C
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFor storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
662041-5MG 04055977261066

Documentation

U-73343 - CAS 142878-12-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

U-73343 - CAS 142878-12-4 - Calbiochem Certificates of Analysis

TitleLot Number
662041

References

Přehled odkazů
Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther. 255, 756.
Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther. 253, 688.

Citations

Název
  • Martha E. O'Donnnell, et al. (2005) Arginine Vasopressin Stimulation of Cerebral Microvascular Endothelial Cell Na-K-Cl Cotransporter Activity is V1 Receptor and [Ca] Dependent. American Journal of Physiology Cell Physiology 289, C283-C292.
  • Di Zhang, et al. (2005) Strontium Promotes Calcium Oscillations in Mouse Meiotic Oocytes and Early Embryos Through InsP3 Receptors, and Requires Activation of Phopsholipase and the Synertistic Action of InsP3. Human Reproduction in press,.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision20-February-2024 JSW
    Synonyms1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione
    DescriptionA cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
    FormOff-white solid
    CAS number142878-12-4
    Chemical formulaC₂₉H₄₂N₂O₃
    Structure formulaStructure formula
    Purity≥98% by TLC
    SolubilityChloroform (200 mg/ml), DMSO (2 mg/ml), or Ethanol (1 mg/ml)
    Storage +15°C to +30°C
    Do Not Freeze Ok to freeze
    Special InstructionsFor storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.
    Toxicity Irritant
    ReferencesTatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
    Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther. 255, 756.
    Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther. 253, 688.
    Citation
  • Martha E. O'Donnnell, et al. (2005) Arginine Vasopressin Stimulation of Cerebral Microvascular Endothelial Cell Na-K-Cl Cotransporter Activity is V1 Receptor and [Ca] Dependent. American Journal of Physiology Cell Physiology 289, C283-C292.
  • Di Zhang, et al. (2005) Strontium Promotes Calcium Oscillations in Mouse Meiotic Oocytes and Early Embryos Through InsP3 Receptors, and Requires Activation of Phopsholipase and the Synertistic Action of InsP3. Human Reproduction in press,.
    		•