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108219 Tris(hydroxymethyl)aminomethan hydrochlorid

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Tris(hydroxymethyl)aminomethan hydrochlorid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 1185-53-1 EC Number: 214-684-5 Molar Mass: 157.60 g/mol Chemical Formula: C₄H₁₁NO₃*ClH Hill Formula: C₄H₁₁NO₃˙ ClH
108219
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Tabulka spec. kláve

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
1185-53-1214-684-5C₄H₁₁NO₃˙ ClHC₄H₁₁NO₃*ClH157.60 g/mol

Products

Katalogové čísloBalení ks/bal.
1082190003 Lepenková krabice 3 x 0,750 kg
1082191003 Plastová láhev 1 kg
1082195000 Plastová láhev 5 kg
1082199010 Plastový sud 10 kg
1082199012 Plastové vedro 12 kg
1082199050 Plastový sud 50 kg
Description
Catalogue Number108219
SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
DescriptionTris(hydroxymethyl)aminomethane hydrochloride
References
Product Information
CAS number1185-53-1
EC number214-684-5
Hill FormulaC₄H₁₁NO₃˙ ClH
Chemical formulaC₄H₁₁NO₃*ClH
Molar Mass157.60 g/mol
HS Code2922 19 99
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.28 g/cm3 (20.2 °C)
Melting Point150.7 °C
pH value4.2 (100 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (50 °C)
Solubility561 g/l rozpustná látka
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Ostatní kapalné a tuhé látky
WGKWGK 1 látka mírně ohrožující vody
Disposal3
Relativně nereaktivní organické reagencie mohou být shromažďovány v kontejneru A. Pokud jsou halogenované, musí být umístěny v kontejneru B. U pevných reziduí použijte kontejner C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageSkladovat od +15°C až +25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Appearancewhite to almost white, crystalline powder
Assay (alkalimetric, calculated on dried substance)≥ 99.0 %
Identity (IR-spectrum)conforms
pH-value (0.5 mol/l, water)3.5 - 5.0
Melting point147 - 153 °C
UV-Absorption (230 nm; 10 %; 1 cm; water)≤ 0.1
UV-Absorption (260 nm; 10 %, 1 cm; water)≤ 0.06
UV-Absorption (280 nm; 10 %; 1 cm; water)≤ 0.06
UV-Absorption (300 nm; 10 %; 1 cm; water)≤ 0.02
UV-Absorption (400 nm; 10 %; 1 cm; water)≤ 0.01
Residual solvents (ICHQ3C) of class 2 (Methanol)≤ 3000 ppm
Residual solvents (ICHQ3C) of class 2 (Nitromethane)≤ 50 ppm
Residual solvents (ICHQ3C) of class 3 (Ethanol)≤ 5000 ppm
Residual solvents (ICHQ3C) of class 3 (Ethylmethylketon)≤ 5000 ppm
Other residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash≤ 0.03
Loss on Drying (105°C)≤ 0.5
Endotoxins< 2.5
Total aerobic microbial count≤ 10²
Total yeast and mould count
≤ 10²
Salmonella spp.
absent in 10 g
E.coli
absent in 1 g
Staphylococcus aureus
absent in 1 g
Pseudomonas aeruginosa
absent in 1 g
Candida albicans
absent in 1 g
Bile tolerante gram negative bacteria
absent in 1 g
DNases (Exo- and endonucleases)
not detected
Proteases
not detected
RNases
not detected
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Total yeast and mould count
≤ 10²
Salmonella spp.
absent in 10 g
E.coli
absent in 1 g
Staphylococcus aureus
absent in 1 g
Pseudomonas aeruginosa
absent in 1 g
Candida albicans
absent in 1 g
Bile tolerante gram negative bacteria
absent in 1 g
DNases (Exo- and endonucleases)
not detected
Proteases
not detected
RNases
not detected
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Global Trade Item Number
Katalogové číslo GTIN
1082190003 04027269296049
1082191003 04027269196462
1082195000 04022536532899
1082199010 04022536702742
1082199012 04027269285586
1082199050 04054839392443

Documentation

Material Qualification Dossier

TitleVersion
6.0

Quality Management Dossier (Open Access)

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Operational Excellence Dossier

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Tris(hydroxymethyl)aminomethan hydrochlorid MSDS

Title

Safety Data Sheet (SDS) 

Tris(hydroxymethyl)aminomethan hydrochlorid Certificates of Analysis

Katalogové číslo BaleníSpecifikaceČíslo šarže
1082190003 Lepenková krabiceSpecifikující dokument ve formátu PDF
1082191003 Plastová láhevSpecifikující dokument ve formátu PDF
1082195000 Plastová láhevSpecifikující dokument ve formátu PDF
1082199010 Plastový sudSpecifikující dokument ve formátu PDF
1082199012 Plastové vedroSpecifikující dokument ve formátu PDF
1082199050 Plastový sudSpecifikující dokument ve formátu PDF

Certificates

Title