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605197 Thrombin-Activatable Fibrinolysis Inhibitor, Human

605197
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Katalogové čísloBalení ks/bal.
605197-50UG Plastová ampulka 50 μg
Description
OverviewNative thrombin-activatable fibrinolysis inhibitor from human liver. Single chain glycoprotein synthesized in the liver. Circulates in plasma as a zymogen at a concentration of 50 nM. Activated by thrombin-thrombomodulin complex by proteolytic cleavage at Arg92. Believed to play an important role in interaction between the procoagulant, anticoagulant, and fibrinolytic systems.
Catalogue Number605197
Brand Family Calbiochem®
SynonymsPlasma Procarboxypeptidase B, TAFI
References
ReferencesBoffa, M.B., et al. 1999. Biochemistry 38, 6547.
Boffa, M.B., et al. 1998. J. Biol. Chem. 273, 2127.
Bajzar, L., et al. 1995. J. Biol. Chem. 270, 14477.
Product Information
Unit of DefinitionOne unit is defined as the amount of enzyme that will hydrolyze 1 µM Hip-L-Arg per min at 25°C, pH 7.65.
FormLiquid
FormulationIn 150 mM NaCl, 20 mM HEPES, pH 7.4.
Quality LevelMQ100
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥2-9 units/mg protein
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Katalogové číslo GTIN
605197-50UG 04055977188431