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616450 TGF-β1, Human Platelets

TGF-β1, Human Platelets MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: hTGF-β1, Transforming Growth Factor-β1

616450
  
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Přehled

Replacement Information

Tabulka spec. kláve

Purity
≥97% by SDS-PAGE
Description
OverviewNative transforming growth factor-β1 from human platelets. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells.
Catalogue Number616450
Brand Family Calbiochem®
SynonymshTGF-β1, Transforming Growth Factor-β1
References
ReferencesLomo, J., et al. 1995. J. Immunol. 154, 1634.
Marushige, K. and Marushige, Y. 1995. Anticancer Res. 14, 2419.
Bermundez, L.E. 1993. J. Immunol. 150, 1838.
Hamilton, J.A., et al. 1993. J. Immunol. 150, 1496.
Reilly, J.T., et al. 1993. Br. J. Haematol. 83, 58.
Sporn, M.B. and Roberts, A.B. 1993. Growth Factors 8, 1.
Product Information
FormLyophilized
FormulationLyophilized from a sterile-filtered solution of 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 40-10 pg/ml as measured by the inhibition of IL-4-dependant proliferation of mouse HT-2 cells using resazurin dye as an indicator of cell proliferation.
Purity≥97% by SDS-PAGE
SourcePrepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
ContaminantsEndotoxin: ≤1 EU/ug of TGF-β1
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C) for short-term storage or freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 1 months at 4°C or up to 3 months at -20°C..
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
616450 0

Documentation

TGF-β1, Human Platelets MSDS

Title

Safety Data Sheet (SDS) 

TGF-β1, Human Platelets Certificates of Analysis

TitleLot Number
616450

References

Přehled odkazů
Lomo, J., et al. 1995. J. Immunol. 154, 1634.
Marushige, K. and Marushige, Y. 1995. Anticancer Res. 14, 2419.
Bermundez, L.E. 1993. J. Immunol. 150, 1838.
Hamilton, J.A., et al. 1993. J. Immunol. 150, 1496.
Reilly, J.T., et al. 1993. Br. J. Haematol. 83, 58.
Sporn, M.B. and Roberts, A.B. 1993. Growth Factors 8, 1.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-May-2008 RFH
SynonymshTGF-β1, Transforming Growth Factor-β1
DescriptionNative transforming growth factor-β1 from human platelets. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigerminal neurinomal cells.
FormLyophilized
FormulationLyophilized from a sterile-filtered solution of 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
SourcePrepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥97% by SDS-PAGE
ContaminantsEndotoxin: ≤1 EU/ug of TGF-β1
Biological activityED₅₀ = 40-10 pg/ml as measured by the inhibition of IL-4-dependant proliferation of mouse HT-2 cells using resazurin dye as an indicator of cell proliferation.
SolubilityReconstitute to a concentration ≥10 µg/ml in sterile 4 mM HCl containing ≥0.1% HSA or BSA.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C) for short-term storage or freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 1 months at 4°C or up to 3 months at -20°C..
Toxicity Standard Handling
Merck USA index14, 9572
ReferencesLomo, J., et al. 1995. J. Immunol. 154, 1634.
Marushige, K. and Marushige, Y. 1995. Anticancer Res. 14, 2419.
Bermundez, L.E. 1993. J. Immunol. 150, 1838.
Hamilton, J.A., et al. 1993. J. Immunol. 150, 1496.
Reilly, J.T., et al. 1993. Br. J. Haematol. 83, 58.
Sporn, M.B. and Roberts, A.B. 1993. Growth Factors 8, 1.

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Kategorie

Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors