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AB9210-25UL Rb Anti-Insulin Degrading Enzyme

AB9210-25UL
25 µL  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Description
Catalogue NumberAB9210-25UL
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionRb Anti-Insulin Degrading Enzyme
Alternate Names
  • IDE
  • Insulysin
  • Insulinase
References
Product Information
FormatSerum
PresentationRabbit serum. Liquid.
Quality LevelMQ100
Applications
ApplicationAnti-Insulin Degrading Enzyme Antibody is an antibody against Insulin Degrading Enzyme for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern blotting: 1:10,000-1:20,000. The antibody recognizes a protein of ~110 kDa on rat liver tissue lysate.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide from rat IDE.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityInsulin Degrading Enzyme (IDE). It is expected that the antibody will also react with human and mouse due to immunogen sequence homology.
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
Gene Symbol
  • IDE
  • Insulysin
  • insulinase
  • insulysin
  • Insulinase
  • FLJ35968
  • INSULYSIN
  • EC 3.4.24.56
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P14735 # May play a role in the cellular processing of insulin. May be involved in intercellular peptide signaling.
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
SIZE: 1019 amino acids; 118022 Da
SUBUNIT: Homodimer (Probable).
SUBCELLULAR LOCATION: Cytoplasm.
PTM: The N-terminus is blocked.
SIMILARITY: SwissProt: P14735 ## Belongs to the peptidase M16 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceTested
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size25 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
AB9210-25UL 04054839337406

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