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554994 RHC-80267 - CAS 83654-05-1 - Calbiochem

554994
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
83654-05-1C₂₀H₃₄N₄O₄

Products

Katalogové čísloBalení ks/bal.
554994-10MG Plastová ampulka 10 mg
Description
OverviewSelective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II (Cat. No. 05-23-0101) and ATP-induced synthesis of 6-keto-prostaglandin F1α.
Catalogue Number554994
Brand Family Calbiochem®
Synonyms1,6-bis(Cyclohexyloximinocarbonylamino)hexane
References
ReferencesShinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295.
Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207.
Konrad, R.J., et al. 1994. Biochemistry 33, 13284.
Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197.
Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.
Product Information
CAS number83654-05-1
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₂₀H₃₄N₄O₄
Chemical formulaC₂₀H₃₄N₄O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetDAG lipase
Primary Target IC<sub>50</sub>4 nM against DAG lipase activity in canine platelets
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
554994-10MG 04055977268355

Documentation

RHC-80267 - CAS 83654-05-1 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

RHC-80267 - CAS 83654-05-1 - Calbiochem Certificates of Analysis

TitleLot Number
554994

References

Přehled odkazů
Shinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295.
Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207.
Konrad, R.J., et al. 1994. Biochemistry 33, 13284.
Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197.
Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-April-2011 RFH
Synonyms1,6-bis(Cyclohexyloximinocarbonylamino)hexane
DescriptionSelective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II and ATP-induced synthesis of 6-keto-prostaglandin F1α.
FormWhite to off-white solid
CAS number83654-05-1
Chemical formulaC₂₀H₃₄N₄O₄
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (25 mg/ml) or ethanol (25 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesShinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295.
Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207.
Konrad, R.J., et al. 1994. Biochemistry 33, 13284.
Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197.
Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.