Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

505881 (R)-(+)-SKF38393 Hydrochloride - CAS 81702-42-3 - Calbiochem

(R)-(+)-SKF38393 Hydrochloride - CAS 81702-42-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Dopamine D₁/D₅ Receptor Partial Agonist, (R)-SKF-38393 Hydrochloride, SKF-38393, SKF38393, SKF 38393

Primary Target: D₁
505881
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
81702-42-3C16H₁₇NO₂•HCl

Products

Katalogové čísloBalení ks/bal.
5.05881.0001 Skleněná láhev 5 mg
Description
OverviewA benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects.
Catalogue Number505881
Brand Family Calbiochem®
SynonymsDopamine D₁/D₅ Receptor Partial Agonist, (R)-SKF-38393 Hydrochloride, SKF-38393, SKF38393, SKF 38393
References
ReferencesTrampus, M. et al. 1993. J. Pharmacol. 235, 83.
Cooper, S. J. et al. 1990. Psychopharmacol. 100, 182.
Dubois, A. et al. 1986. Neurosci. 19, 125.
Kaiser, C. C. et al. 1982. J. Med. Chem. 25, 697.
Product Information
CAS number81702-42-3
FormWhite solid
Hill FormulaC16H₁₇NO₂•HCl
Chemical formulaC16H₁₇NO₂•HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetD₁
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
5.05881.0001 04055977263176

Documentation

(R)-(+)-SKF38393 Hydrochloride - CAS 81702-42-3 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Přehled odkazů
Trampus, M. et al. 1993. J. Pharmacol. 235, 83.
Cooper, S. J. et al. 1990. Psychopharmacol. 100, 182.
Dubois, A. et al. 1986. Neurosci. 19, 125.
Kaiser, C. C. et al. 1982. J. Med. Chem. 25, 697.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2013 JSW
SynonymsDopamine D₁/D₅ Receptor Partial Agonist, (R)-SKF-38393 Hydrochloride, SKF-38393, SKF38393, SKF 38393
DescriptionA benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects.
FormWhite solid
CAS number81702-42-3
Chemical formulaC16H₁₇NO₂•HCl
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (100 mM)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesTrampus, M. et al. 1993. J. Pharmacol. 235, 83.
Cooper, S. J. et al. 1990. Psychopharmacol. 100, 182.
Dubois, A. et al. 1986. Neurosci. 19, 125.
Kaiser, C. C. et al. 1982. J. Med. Chem. 25, 697.