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506044 Muscimol - CAS 2763-96-4 - Calbiochem

Muscimol is a constituent and psychoactive ingredient of the mushroom Amanita muscaria, that acts as a potent agonist of GABAA receptors.

Muscimol - CAS 2763-96-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GABAA Receptor Agonist, Muscimol

Primary Target: GABAA
506044
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
2763-96-4C₄H₆N₂O₂

Products

Katalogové čísloBalení ks/bal.
5.06044.0001 Skleněná láhev 1 mg
Description
OverviewA constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28 µM and 33 µM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
Catalogue Number506044
Brand Family Calbiochem®
SynonymsGABAA Receptor Agonist, Muscimol
References
ReferencesChandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
Fischer, H., et al. 2005. J. Physiol. 564, 465.
Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.
Product Information
CAS number2763-96-4
FormWhite solid
Hill FormulaC₄H₆N₂O₂
Chemical formulaC₄H₆N₂O₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetGABAA
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 28

Very toxic if swallowed.
S PhraseS: 46

If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
5.06044.0001 04055977262667

Documentation

Muscimol - CAS 2763-96-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Přehled odkazů
Chandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
Fischer, H., et al. 2005. J. Physiol. 564, 465.
Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2013 JSW
SynonymsGABAA Receptor Agonist, Muscimol
DescriptionA constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28 µM and 33 µM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
FormWhite solid
CAS number2763-96-4
Chemical formulaC₄H₆N₂O₂
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Toxic
ReferencesChandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
Fischer, H., et al. 2005. J. Physiol. 564, 465.
Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.