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FCABS165A6 Sigma-AldrichMilli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate

Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.

Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA

Research Category: Signaling Research Sub-Category: MAP Kinases Gene Symbol: MAPK1, p38, ERK, P42MAPK, ERK2, p40, PRKM1, p41mapk, PRKM2, MAPK2, p42-MAPK, p41, ERK-2, ERT1 UniProt Number: P21708

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Tabulka spec. kláve

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	FC	Rb	AlexaFluor®647	Polyclonal Antibody

Description
Catalogue Number	FCABS165A6
Trade Name	Milli-Mark
Description	Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate
Alternate Names	Extracellular signal-regulated kinase 1 ERK-1 Insulin-stimulated MAP2 kinase Mitogen-activated protein kinase 1 MAP kinase 1 MAPK 1 p44-ERK1 ERT2 MAP kinase isoform p44 p44 MAPK Microtubule-associated protein 2 kinase MNK1
Background Information	The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.

References

Product Information
Format	AlexaFluor®647
Control	Jurkat cells
Presentation	Purified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide
Quality Level	MQ100

Applications
Application	Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.
Key Applications	Flow Cytometry

Biological Information
Immunogen	KLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.
Epitope	C-terminus
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Rabbit
Specificity	Antibody recognizes MAPK1/2. C-terminus.
Species Reactivity	Human
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NP_059043
Entrez Gene Summary	Kinase involved in intracellular signalling; component of Mapk signalling pathway [RGD]
Gene Symbol	MAPK1 p38 ERK P42MAPK ERK2 p40 PRKM1 p41mapk PRKM2 MAPK2 p42-MAPK p41 ERK-2 ERT1
Purification Method	Protein A Purfied
UniProt Number	P21708
UniProt Summary	FUNCTION: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4 (HSF4) By similarity
Molecular Weight	43 kDa Calculated

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by flow cytometry using Jurkat cells
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Packaging Information
Material Size	100 tests

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
Katalogové číslo	GTIN
FCABS165A6	04053252411984

Documentation

Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate MSDS

Title
Safety Data Sheet (SDS)

Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate Certificates of Analysis

Title	Lot Number
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor#174; 647 Conjugate - 2197289	2197289
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor#174; 647 Conjugate - NRG1772829	NRG1772829
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate	3063882
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 3173841	3173841
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 3981703	3981703
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate -2750262	2750262
Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 2420521	2420521

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Kategorie

Life Science Research > Antibodies and Assays > Primary Antibodies

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