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234376 Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli

Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhM-CSF

234376
  
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Přehled

Replacement Information
Description
Overview

This product has been discontinued.



Recombinant, human macrophage colony-stimulating factor expressed in E. coli. Stimulates formation of macrophage colonies from bone marrow hematopoietic progenitor cells. Increases osteoclastic bone resorption in adults. Induces cell death in HIV-1 infected monocytes.
Catalogue Number234376
Brand Family Calbiochem®
SynonymsrhM-CSF
References
ReferencesEdwards, M., et al. 1998. Bone 22, 325.
Bergamini, A., et al. 1994. Immunol. Lett. 42, 35.
Hattersley, G., et al. 1991. Biochem. Biophys. Res. Commun. 177, 526.
Product Information
CAS number81627-83-0
FormLyophilized
FormulationLyophilized from sterile-filtered PBS, 50 µg of BSA/µg M-CSF.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 0.5-1.5 ng/ml as measured in a cell proliferation assay using the M-CSF-dependent mouse monocytic cell line, M-NFS-60
Purity≥97% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <1.0 EU/µg M-CSF
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGI5500000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for 1 month at 4°C or for 3 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
234376 0

Documentation

Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli MSDS

Title

Safety Data Sheet (SDS) 

Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
234376

References

Přehled odkazů
Edwards, M., et al. 1998. Bone 22, 325.
Bergamini, A., et al. 1994. Immunol. Lett. 42, 35.
Hattersley, G., et al. 1991. Biochem. Biophys. Res. Commun. 177, 526.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision09-June-2008 RFH
SynonymsrhM-CSF
DescriptionRecombinant, human macrophage colony-stimulating factor expressed in E. coli. Stimulates formation of macrophage colonies from bone marrow hematopoietic progenitor cells. Induces cell death in HIV-1 infected monocytes. Human M-CSF is active in murine systems and the recombinant cytokine is indistinguishable from the natural M-CSF in all biological assays tested.
FormLyophilized
FormulationLyophilized from sterile-filtered PBS, 50 µg of BSA/µg M-CSF.
CAS number81627-83-0
RTECSGI5500000
Purity≥97% by SDS-PAGE
ContaminantsEndotoxin: <1.0 EU/µg M-CSF
Biological activityED₅₀ = 0.5-1.5 ng/ml as measured in a cell proliferation assay using the M-CSF-dependent mouse monocytic cell line, M-NFS-60
SolubilityReconstitute to a concentration of ≥1 mg/ml with sterile PBS containing ≥0.1% HSA or BSA.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for 1 month at 4°C or for 3 months at -70°C.
Toxicity Standard Handling
ReferencesEdwards, M., et al. 1998. Bone 22, 325.
Bergamini, A., et al. 1994. Immunol. Lett. 42, 35.
Hattersley, G., et al. 1991. Biochem. Biophys. Res. Commun. 177, 526.

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Katalogové číslo Popis
234378 Macrophage Colony-Stimulating Factor, Mouse, Recombinant, E. coli