Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

504635 MPEP Hydrochloride - CAS 96206-92-7 - Calbiochem

MPEP Hydrochloride - CAS 96206-92-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 6-Methyl-2-(phenylethynyl)pyridine hydrochloride

Primary Target: mGlu₅ receptors
504635
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
96206-92-7C₁₄H₁₁N Å• HCl
Description
Overview

This product has been discontinued.



A non-competitive, highly potent antagonist selective for mGlu5 receptors (IC50 = 36 nM). Also a positive allosteric modulator of mGlu4and weak anatagonist of NMDA receptors. Biologically active admitted systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as learning and memory, sleep, neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease.
Catalogue Number504635
Brand Family Calbiochem®
Synonyms6-Methyl-2-(phenylethynyl)pyridine hydrochloride
References
ReferencesManago, F., et al. 2013. Psychopharmacol. (Berl) 226, 541.
Cavas, M., et al. 2013. Prog. Neuropsychopharmacol. Biol. Psychiatry. 40, 18.
Micheli, F., 2000. Cur. Op. Invest. Drugs (London, England) 1, 355.
Li, X., et al. 2006. J. Pharmacol. & Exp. Therapeutics. 319, 254.
Tatarczyñska, E., et al. 2001. Bri. J. Pharmacol. 132, 1423.
Product Information
CAS number96206-92-7
FormWhite to off-white solid
Hill FormulaC₁₄H₁₁N Å• HCl
Chemical formulaC₁₄H₁₁N Å• HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetmGlu₅ receptors
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze 9-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
504635 0

Documentation

MPEP Hydrochloride - CAS 96206-92-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Přehled odkazů
Manago, F., et al. 2013. Psychopharmacol. (Berl) 226, 541.
Cavas, M., et al. 2013. Prog. Neuropsychopharmacol. Biol. Psychiatry. 40, 18.
Micheli, F., 2000. Cur. Op. Invest. Drugs (London, England) 1, 355.
Li, X., et al. 2006. J. Pharmacol. & Exp. Therapeutics. 319, 254.
Tatarczyñska, E., et al. 2001. Bri. J. Pharmacol. 132, 1423.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision24-August-2020 JSW
Synonyms6-Methyl-2-(phenylethynyl)pyridine hydrochloride
DescriptionA non-competitive, highly potent antagonist selective for mGlu5 receptors (IC50 = 36 nM). Also a positive allosteric modulator of mGlu4and weak anatagonist of NMDA receptors. Biologically active admitted systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as learning and memory, sleep, neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease.
FormWhite to off-white solid
CAS number96206-92-7
Chemical formulaC₁₄H₁₁N Å• HCl
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze 9-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesManago, F., et al. 2013. Psychopharmacol. (Berl) 226, 541.
Cavas, M., et al. 2013. Prog. Neuropsychopharmacol. Biol. Psychiatry. 40, 18.
Micheli, F., 2000. Cur. Op. Invest. Drugs (London, England) 1, 355.
Li, X., et al. 2006. J. Pharmacol. & Exp. Therapeutics. 319, 254.
Tatarczyñska, E., et al. 2001. Bri. J. Pharmacol. 132, 1423.