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444237 MMP-8 Inhibitor I - CAS 236403-25-1 - Calbiochem

The MMP-8 Inhibitor I, also referenced under CAS 236403-25-1, controls the biological activity of MMP-8. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MMP-8 Inhibitor I - CAS 236403-25-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (3R)-(+)-[2-(4-Methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-hydroxamate]

Primary Target: MMP-8
444237
  
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
236403-25-1C₁₇H₁₈N₂O₅S
Description
Overview

This product has been discontinued.



A potent and cell-permeable inhibitor of MMP-8 (IC50 = 4 nM).
Catalogue Number444237
Brand Family Calbiochem®
Synonyms(3R)-(+)-[2-(4-Methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-hydroxamate]
References
ReferencesPrager, G.W., et al. 2004. Blood 103, 955.
Matter, H., et al. 1999. J. Med. Chem. 42, 1908.
Product Information
CAS number236403-25-1
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₇H₁₈N₂O₅S
Chemical formulaC₁₇H₁₈N₂O₅S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-8
Primary Target IC<sub>50</sub>4 nM
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
444237 0

Documentation

MMP-8 Inhibitor I - CAS 236403-25-1 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

MMP-8 Inhibitor I - CAS 236403-25-1 - Calbiochem Certificates of Analysis

TitleLot Number
444237

References

Přehled odkazů
Prager, G.W., et al. 2004. Blood 103, 955.
Matter, H., et al. 1999. J. Med. Chem. 42, 1908.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-April-2011 RFH
Synonyms(3R)-(+)-[2-(4-Methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-hydroxamate]
DescriptionA cell-permeable, potent inhibitor of MMP-8 (neutrophil collagenase; IC50 = 4 nM).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number236403-25-1
Chemical formulaC₁₇H₁₈N₂O₅S
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (200 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesPrager, G.W., et al. 2004. Blood 103, 955.
Matter, H., et al. 1999. J. Med. Chem. 42, 1908.