475847 Sigma-AldrichMIF Antagonist IV, RDR 03785 - Calbiochem
The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.
More>> The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications. Less<<MIF Antagonist IV, RDR 03785 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Macrophage Migration Inhibitory Factor Antagonist IV, 6-(Morpholino(4-(trifluoromethyl)phenyl)methyl)-1,3-benzodioxol-5-ol
Recommended Products
Přehled
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Tabulka spec. kláve
| Empirical Formula |
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| C₁₉H₁₈F₃NO₄ |
| Description | |
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| Overview | A cell-permeable morpholino-benzodioxol compound that inhibits MIF tautomerase activity (Ki and IC50 = 0.57 and 2.4 µM, respectively) via direct non-covalent MIF interaction (KD = 24.5 µM). RDR 03758 at 10 µM is shown to completely neutralize the overriding effect of 100 ng/ml MIF on the inhibition of LPS-stimulated TNF production by dexamethasone (Cat. No. 265005) in RAW 264.7 marcophage cultures. |
| Catalogue Number | 475847 |
| Brand Family | Calbiochem® |
| Synonyms | Macrophage Migration Inhibitory Factor Antagonist IV, 6-(Morpholino(4-(trifluoromethyl)phenyl)methyl)-1,3-benzodioxol-5-ol |
| References | |
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| References | Ouertatani-Sakouhi, H., et al. 2010. J. Biol. Chem. 285, 26581. |
| Product Information | |
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| Form | Cream solid |
| Hill Formula | C₁₉H₁₈F₃NO₄ |
| Chemical formula | C₁₉H₁₈F₃NO₄ |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥97% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Katalogové číslo | GTIN |
| 475847 | 0 |
Documentation
MIF Antagonist IV, RDR 03785 - Calbiochem MSDS
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MIF Antagonist IV, RDR 03785 - Calbiochem Certificates of Analysis
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| 475847 |
References
| Přehled odkazů |
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| Ouertatani-Sakouhi, H., et al. 2010. J. Biol. Chem. 285, 26581. |
Brochure
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| New Products: Volume 3, 2012 |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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