MDM2 Antibodies

Millipore’s MDM2 antibodies demonstrate specificity against MDM2, nuclear phosphoprotein with multiple variants. See below for MDM2 antibodies, based on the expertise of Upstate & Chemicon.  Více

Millipore’s MDM2 antibodies demonstrate specificity against MDM2, nuclear phosphoprotein with multiple variants. See below for MDM2 antibodies, based on the expertise of Upstate & Chemicon. Méně

Overexpression of MDM2 is characteristic of many tumors. IT MDM2 is a nuclear phosphoprotein that inhibits transactivation by p52. MDM2’s principal function is the ubiquitination and degradation of p53 tumor suppressor protein. MDM2 affects tumorigenesis, apoptosis, and the cell cycle. There are at least 40 separate splice variants identified to date.  More>>

Overexpression of MDM2 is characteristic of many tumors. IT MDM2 is a nuclear phosphoprotein that inhibits transactivation by p52. MDM2’s principal function is the ubiquitination and degradation of p53 tumor suppressor protein. MDM2 affects tumorigenesis, apoptosis, and the cell cycle. There are at least 40 separate splice variants identified to date. Less<<