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505027 Kynurenic Acid Sodium Salt - CAS 196901 - Calbiochem

Kynurenic Acid Sodium Salt - CAS 196901 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ionotropic Glutamate Receptor Antagonist, Kynurenic Acid Sodium Salt, 4-Hydroxyquinoline-2-carboxylic acid sodium salt

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Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
2439-02-3C₁₀H₆NNaO₃
Description
Overview

This product has been discontinued.



An endogenous antagonist of ionotropic AMPA, NMDA and kainate glutamate receptors, a noncompetitive antagonist at the glycine site of the NMDA receptor, and a ligand for the orphan G protein-coupled receptor GPR35. Often used for blocking kainic acid neurotoxicity. Proposed to be involved in the pathophysiology and pathogenesis of schizophrenia.
Catalogue Number505027
Brand Family Calbiochem®
SynonymsIonotropic Glutamate Receptor Antagonist, Kynurenic Acid Sodium Salt, 4-Hydroxyquinoline-2-carboxylic acid sodium salt
References
ReferencesSchwarcz, R., et al. 2010. Neuropsychopharmacol. 35, 1734.
Mok, H., et al. 2009. Neuropharmacol. 57, 242.
Erhardt, S., et al. 2007. Physiol. Behav. 92, 203.
Wang, J., et al. 2006. J. Biol. Chem. 281, 22021.
Stone, W., 1993. Pharmacol. Rev. 45, 309.
Product Information
CAS number2439-02-3
FormOff-white solid
Hill FormulaC₁₀H₆NNaO₃
Chemical formulaC₁₀H₆NNaO₃
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
505027 0

Documentation

Kynurenic Acid Sodium Salt - CAS 196901 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Přehled odkazů
Schwarcz, R., et al. 2010. Neuropsychopharmacol. 35, 1734.
Mok, H., et al. 2009. Neuropharmacol. 57, 242.
Erhardt, S., et al. 2007. Physiol. Behav. 92, 203.
Wang, J., et al. 2006. J. Biol. Chem. 281, 22021.
Stone, W., 1993. Pharmacol. Rev. 45, 309.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-April-2016 JSW
SynonymsIonotropic Glutamate Receptor Antagonist, Kynurenic Acid Sodium Salt, 4-Hydroxyquinoline-2-carboxylic acid sodium salt
DescriptionAn endogenous antagonist of ionotropic AMPA, NMDA and kainate glutamate receptors, a noncompetitive antagonist at the glycine site of the NMDA receptor, and a ligand for the orphan G protein-coupled receptor GPR35. Often used for blocking kainic acid neurotoxicity. Proposed to be involved in the pathophysiology and pathogenesis of schizophrenia.
FormOff-white solid
CAS number2439-02-3
Chemical formulaC₁₀H₆NNaO₃
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSchwarcz, R., et al. 2010. Neuropsychopharmacol. 35, 1734.
Mok, H., et al. 2009. Neuropharmacol. 57, 242.
Erhardt, S., et al. 2007. Physiol. Behav. 92, 203.
Wang, J., et al. 2006. J. Biol. Chem. 281, 22021.
Stone, W., 1993. Pharmacol. Rev. 45, 309.