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508773 InSolution™ PPACK, 2HCl - CAS 82188-90-7 - Calbiochem

A 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl in H₂O.

InSolution™ PPACK, 2HCl - CAS 82188-90-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution™

Primary Target: Thrombin
508773
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
82188-90-7C₂₁H₃₁ClN₆O₃ • 2HCl

Products

Katalogové čísloBalení ks/bal.
5.08773.0001 Skleněná láhev 5 mg
Description
Catalogue Number508773
Brand Family Calbiochem®
SynonymsD-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution™
References
ReferencesRosado, J. A., et al. 2002. J. Biol. Chem. 277, 42157.
Odake S., et al. 1995. J. Enzyme Inhib. 9, 17.
Arni, R.K., et al. 1993. Biochemistry 32, 4727.
Yamashita, T., et al. 1993. Thromb. Res. 69, 93.
Schmaier, A.H., et al. 1992. Thromb. Res. 67, 479.
Collen, D., et al. 1982. J. Lab. Clin. Med. 99, 76.
Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Kettner, C., and Shaw, E. 1979. Thromb. Res. 14, 969.
Product Information
CAS number82188-90-7
FormLiquid
FormulationA 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl (Cat. No. 520222) in H₂O.
Hill FormulaC₂₁H₃₁ClN₆O₃ • 2HCl
Chemical formulaC₂₁H₃₁ClN₆O₃ • 2HCl
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Target Thrombin
Purity≥88% by HPLC
Physicochemical Information
Peptide SequenceH-D-Phe-Pro-Arg-chloromethylketone, 2HCl
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Protect from Light Protect from light
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
5.08773.0001 04055977261394

Documentation

InSolution™ PPACK, 2HCl - CAS 82188-90-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

InSolution™ PPACK, 2HCl - CAS 82188-90-7 - Calbiochem Certificates of Analysis

TitleLot Number
508773

References

Přehled odkazů
Rosado, J. A., et al. 2002. J. Biol. Chem. 277, 42157.
Odake S., et al. 1995. J. Enzyme Inhib. 9, 17.
Arni, R.K., et al. 1993. Biochemistry 32, 4727.
Yamashita, T., et al. 1993. Thromb. Res. 69, 93.
Schmaier, A.H., et al. 1992. Thromb. Res. 67, 479.
Collen, D., et al. 1982. J. Lab. Clin. Med. 99, 76.
Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Kettner, C., and Shaw, E. 1979. Thromb. Res. 14, 969.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-September-2017 JSW
SynonymsD-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution™
DescriptionExtremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator. Factor VIIa, and Factor XIa.
FormLiquid
FormulationA 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl (Cat. No. 520222) in H₂O.
Intert gas (Yes/No) Packaged under inert gas
CAS number82188-90-7
Chemical formulaC₂₁H₃₁ClN₆O₃ • 2HCl
Peptide SequenceH-D-Phe-Pro-Arg-chloromethylketone, 2HCl
Purity≥88% by HPLC
Storage Protect from light
Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesRosado, J. A., et al. 2002. J. Biol. Chem. 277, 42157.
Odake S., et al. 1995. J. Enzyme Inhib. 9, 17.
Arni, R.K., et al. 1993. Biochemistry 32, 4727.
Yamashita, T., et al. 1993. Thromb. Res. 69, 93.
Schmaier, A.H., et al. 1992. Thromb. Res. 67, 479.
Collen, D., et al. 1982. J. Lab. Clin. Med. 99, 76.
Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Kettner, C., and Shaw, E. 1979. Thromb. Res. 14, 969.