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402096 INDO 1/AM

Cell-permeable ester derivative of INDO 1.

INDO 1/AM MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Pentaacetoxymethyl Ester

402096
  
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
112926-02-0C₄₇H₅₁N₃O₂₂
Description
Overview

This product has been discontinued.



Cell-permeable ester derivative of INDO 1. After crossing the cell membrane, INDO 1/AM is rapidly hydrolyzed by cytoplasmic esterases and remains trapped within the cell. Can be used to selectively monitor Ca2+ levels in mitochondria and in the cytosol. It is insensitive to Mg2+. Note: 1 set = 10 x 100 µg.
Catalogue Number402096
Brand Family Calbiochem®
Synonyms1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Pentaacetoxymethyl Ester
References
ReferencesZhou, Z., et al. 1998. J. Physiol. 507, 379.
Griffiths, E.J., et al. 1997. Am. J. Physiol. 273, C37.
Grierson, J.P., et al. 1992. J. Neurophysiol. 67, 704.
Lopez, M., et al. 1989. Cytometry 10, 165.
Product Information
CAS number112926-02-0
ATP CompetitiveN
FormYellow solid
Hill FormulaC₄₇H₅₁N₃O₂₂
Chemical formulaC₄₇H₅₁N₃O₂₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMonitor Ca2+ levels in mitochondria and in the cytosol
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Emission max.
Excitation max.
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
402096 0

Documentation

INDO 1/AM MSDS

Title

Safety Data Sheet (SDS) 

INDO 1/AM Certificates of Analysis

TitleLot Number
402096

References

Přehled odkazů
Zhou, Z., et al. 1998. J. Physiol. 507, 379.
Griffiths, E.J., et al. 1997. Am. J. Physiol. 273, C37.
Grierson, J.P., et al. 1992. J. Neurophysiol. 67, 704.
Lopez, M., et al. 1989. Cytometry 10, 165.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Fluorescent Calcium Probes Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-July-2016 JSW
Synonyms1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Pentaacetoxymethyl Ester
DescriptionCell-permeable ester derivative of INDO 1 (Cat. No. 402095). After crossing the cell membrane, INDO 1/AM is rapidly hydrolyzed by cytoplasmic esterases and remains trapped within the cell. Spectral properties in the presence of low calcium concentrations (ex. 349 nm, em. 485 nm) differ from those during high calcium conditions (ex. 330 nm, em. 398 nm). Note: 1 set = 10 x 100 µg.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number112926-02-0
Chemical formulaC₄₇H₅₁N₃O₂₂
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (10 mg/ml). PLURONIC® F-127 (Cat. No. 540025) can be used to aid in the dispersion and solubilization.
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesZhou, Z., et al. 1998. J. Physiol. 507, 379.
Griffiths, E.J., et al. 1997. Am. J. Physiol. 273, C37.
Grierson, J.P., et al. 1992. J. Neurophysiol. 67, 704.
Lopez, M., et al. 1989. Cytometry 10, 165.