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370665 Guanosine-3ʹ-5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Triethylammonium Salt - Calbiochem

370665
  
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Tabulka spec. kláve

Empirical Formula
C₁₆H₁₄ClN₅O₇PS · (CH₃CH₂)₃NH
Description
OverviewSelective membrane-permeable activator of protein kinase G that has a higher activation potential than cGMP. Does not significantly affect cGMP-regulated phosphodiesterases. Inhibits the thrombin-induced phosphorylation of human platelets mediated by myosin light chain kinase (MLCK) and protein kinase C (PKC). Note: 25 µmol = 14.73 mg.
Catalogue Number370665
Brand Family Calbiochem®
Synonyms8-pCPT-cGMP, TEA
References
ReferencesAlioua, A., et al. 1998. J. Biol. Chem. 273, 32950.
Draijer, R., et al. 1995. Circ. Res. 77, 895.
Geiger, J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 1031.
Wolfe, L., et al. 1989. J. Biol. Chem. 264, 7734.
Product Information
ATP CompetitiveN
FormLyophilized
Hill FormulaC₁₆H₁₄ClN₅O₇PS · (CH₃CH₂)₃NH
Chemical formulaC₁₆H₁₄ClN₅O₇PS · (CH₃CH₂)₃NH
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetProtein kinase G
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Katalogové číslo GTIN
370665 0