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227036 Cholera Toxin, Vibrio cholerae, Type Inaba 569B, Azide Free - CAS 9012-63-9 - Calbiochem

Cholera toxin Inaba 569B, CAS 9012-63-9, has a single A subunit surrounded by five polypeptides chains of the B subunits. The A subunit catalyzes the ADP-ribosylation of the α-subunit of G-proteins.

Cholera Toxin, Vibrio cholerae, Type Inaba 569B, Azide Free - CAS 9012-63-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
227036
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Přehled

Tabulka spec. kláve

CAS #
9012-63-9

Products

Katalogové čísloBalení ks/bal.
227036-1MG Skleněná láhev 1 mg
Přidat k oblíbeným položkám
Description
OverviewUseful for studies involving adenylate cyclase, AMP, and related membrane-transport phenomena. Consists of a single A subunit surrounded by five polypeptide chains of the B subunits. The A subunit catalyzes the ADP-ribosylation of the α-subunit of G-proteins, reducing intrinsic GTPase activity and activating the α-subunit. The B subunits are responsible for the attachment of the native toxin on the cell surface.
Useful for tissue culture applications.
Catalogue Number227036
Brand Family Calbiochem®
References
ReferencesGilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
Product Information
CAS number9012-63-9
ActivityBinding activity is assessed by hemagglutination assay using trisialoganglioside fixed sheep red blood cells.
ATP CompetitiveN
DeclarationNot available for sale outside of the United States.
FormSolid
FormulationLyophilized from 200 mM NaCl, 50 mM Tris, 1 mM EDTA, pH 7.5.
ReversibleN
Quality LevelMQ100
Biological Information
Primary Targetα-subunit of G-proteins
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Cell permeableN
Safety Information according to GHS
RTECSLF3100000
Safety Information
R PhraseR: 21/22-36/37/38

Harmful in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
S PhraseS: 7-36/37

Keep container tightly closed.
Wear suitable protective clothing and gloves.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Do not freeze Yes
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C under sterile conditions.
End use certificateY
Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
Global Trade Item Number
Katalogové číslo GTIN
227036-1MG 04055977200560