203704 Sigma-AldrichBPIQ-II
A cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC₅₀ = 8 pM).
More>> A cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC₅₀ = 8 pM). Less<<BPIQ-II MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 8-[(3-Bromophenyl)amino]-1H-imidazo[4,5-g]-quinazoline
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Přehled
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Tabulka spec. kláve
| CAS # | Empirical Formula |
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| 171179-32-1 | C₁₅H₁₀BrN₅ |
| References | |
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| References | Rewcastle, G.W., et al. 1996. J. Med. Chem. 39, 918. |
| Product Information | |
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| CAS number | 171179-32-1 |
| Form | Pale pink solid |
| Hill Formula | C₁₅H₁₀BrN₅ |
| Chemical formula | C₁₅H₁₀BrN₅ |
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| Biological Information | |
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| Primary Target | EGFR |
| Primary Target IC<sub>50</sub> | 8 pM |
| Secondary target | growth factor mediated mitogenisis in swiss 3T3 cells (Ki = 46 nM) |
| Purity | ≥95% by HPLC |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Katalogové číslo | GTIN |
| 203704 | 0 |
Documentation
BPIQ-II Certificates of Analysis
| Title | Lot Number |
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| 203704 |
References
| Přehled odkazů |
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| Rewcastle, G.W., et al. 1996. J. Med. Chem. 39, 918. |