203696 BPIQ-I
A cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC₅₀ = 25 pM).
More>> A cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC₅₀ = 25 pM). Less<<Synonyms: 8-[(3-Bromophenyl)amino]-3-methyl-3H-imidazo[4,5-g]-quinazoline
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Přehled
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Tabulka spec. kláve
CAS # | Empirical Formula |
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174709-30-9 | C₁₆H₁₂BrN₅ |
References | |
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References | Rewcastle, G.W., et al. 1996. J. Med. Chem. 39, 918. |
Product Information | |
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CAS number | 174709-30-9 |
ATP Competitive | Y |
Form | Off-white solid |
Hill Formula | C₁₆H₁₂BrN₅ |
Chemical formula | C₁₆H₁₂BrN₅ |
Reversible | Y |
Structure formula Image |
Applications |
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Biological Information | |
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Primary Target | EGFR |
Primary Target IC<sub>50</sub> | 25 pM against tyrosine kinase activity of the epidermal growth factor receptor (EGFR) |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
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Materials Information |
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Safety Information according to GHS |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Katalogové číslo | GTIN |
203696 | 0 |
Documentation
BPIQ-I Certificates of Analysis
Title | Lot Number |
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203696 |
References
Přehled odkazů |
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Rewcastle, G.W., et al. 1996. J. Med. Chem. 39, 918. |