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ABC834 Anti-ZIP-6 Antibody

Anti-ZIP-6 Antibody detects level of ZIP-6 & has been published & validated for use in ZIP-6.

Anti-ZIP-6 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: SLC39A6, LIV1, ZIP6 UniProt Number: Q13433
ABC834
100 µg  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC834
DescriptionAnti-ZIP-6 Antibody
Alternate Names
  • Zinc transporter ZIP6
  • Estrogen-regulated protein LIV-1
  • Solute carrier family 39 member 6
  • Zrt- and Irt-like protein 6
  • ZIP-6
Background InformationZinc transporter ZIP6, also known as Estrogen-regulated protein LIV-1 or Solute carrier family 39 member 6 orZrt- and Irt-like protein 6 (ZIP-6), and encoded by the gene name ZIP6 or SLC39A6 or LIV1 is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP-6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP-6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP-6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP-6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-ZIP-6 Antibody detects level of ZIP-6 & has been published & validated for use in ZIP-6.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: 5 μg/mL from a representative lot detected Anti-ZIP-6 in mouse lung tissue.
Biological Information
ImmunogenKLH-conjugated synthetic peptide corresponding to the center region of human Anti-ZIP-6.
Epitopecenter region
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody is recognizes isoforms at ~48 and ~85 kDa and is predicted to not cross-react with other ZIP family members.
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • SLC39A6
  • LIV1
  • ZIP6
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~48 and ~85 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 2 isoforms produced by alternative splicing at ~49 kDa and ~85 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse lung tissue lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected Anti-ZIP-6 in mouse lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ABC834 04053252943911