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ABN415 Anti-TRAPPC1 Antibody

ABN415
100 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN415
DescriptionAnti-TRAPPC1 Antibody
Alternate Names
  • TRAPPC-1
  • Trafficking protein particle complex subunit 1
  • BET5 homolog
  • Multiple myeloma protein 2
  • MUM-2
  • MUM2
Background InformationTRAPPC1 is one part of a larger protein complex called the TRAPP (transport protein particle) complex vital to Golgi function and transport. TRAPPC1 is localized to the Golgi and endoplasmic reticulum. Vesicle-mediated transport is a process carried out by virtually all cells and is required for the proper targeting and secretion of proteins. As such, there are numerous proteins involved to ensure that the proteins are properly transported, targeted, tethered, and localized. The TRAPP complex is just one such complex but it is one of the most studied. Mutations in TRAPPC proteins can lead to serious disorders including muscular dystrophy and myopathy such as that seen with mutations associated with TRAPPC11 (a related gene to TRAPPC1).
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-TRAPPC1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of TRAPPC1.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: 0.25 µg/mL from a representative lot detected TRAPPC1 in 5 µg of mouse brain tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TRAPPC1 in human cerebral cortex, cerebellum, and kidney.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the Near C-terminus of Human TRAPPC1.
EpitopeNear C-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Monkey based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • BET5
  • MUM2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~19 kDa observed. The endogenous band appears at ~31kDa (mouse brain) while the transfected band appears at ~19kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in TRAPPC1 transfected HEK293T cell lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected TRAPPC1 in 5 µg of TRAPPC1 transfected HEK293T cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ABN415 04055977052909