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574660 Anti-Survivin Rabbit pAb

This Anti-Survivin Rabbit pAb is validated for use in ELISA, Immunoblotting, Immunofluorescence, Immunohistochemistry for the detection of Survivin.

Anti-Survivin Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Inhibitor of Apoptosis Protein, Anti-TIAP

574660
  
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Přehled

Replacement Information

Tabulka spec. kláve

Host
Rb
Description
OverviewRecognizes the ~16.5 kDa survivin protein. Does not cross-react with EPR-1.
  • Antibody Target Gene Symbol: BIRC5
  • Target Synonym: AAC-11, AP14, API4, EPR-1, SURVIVIN, SURVIVIN 2B, Survivin delta ex3, survivin40, TIAP
  • Entrez Gene Name: baculoviral IAP repeat-containing 5
  • Hu Entrez ID: 332 (Related Antibodies: PC527)
  • Mu Entrez ID: 11799
  • Rat Entrez ID: 64041

    • This product has been discontinued.
    Catalogue Number574660
    Brand Family Calbiochem®
    SynonymsAnti-Inhibitor of Apoptosis Protein, Anti-TIAP
    References
    ReferencesAdida, C., et al. 1998. Am. J. Pathol.152, 43.
    Li, F., et al. 1998. Nature 396, 580.
    Lu, C.-D., et al. 1998. Cancer Res. 58, 1808.
    Ambrosini, G., et al. 1997. Nature Med. 3, 917.
    Product Information
    FormLiquid
    FormulationIn PBS, 0.1% BSA.
    Preservative≤0.1% sodium azide
    Applications
    Key Applications Enzyme-Linked Immunosorbent Assay
    Immunoblotting (Western Blotting)
    Immunofluorescence
    Immunohistochemistry
    Application NotesELISA (1:10,000-1:100,000)
    Immunoblotting (1-10 µg/ml, chemiluminescence)
    Immunofluorescence (2-20 µg/ml)
    Immunohistochemistry (2-20 µg/ml)
    Application CommentsDoes not cross-react with EPR-1. Variables associated with assay conditions will dictate the optimal working dilution.
    Biological Information
    Immunogena synthetic peptide corresponding to amino acids near the C-terminus of human survivin
    ImmunogenHuman
    HostRabbit
    IsotypeIgG
    Concentration Label Please refer to vial label for lot-specific concentration
    Physicochemical Information
    Dimensions
    Materials Information
    Toxicological Information
    Safety Information according to GHS
    Safety Information
    Product Usage Statements
    Storage and Shipping Information
    Ship Code Dry Ice Only
    Toxicity Standard Handling
    Storage -20°C
    Avoid freeze/thaw Avoid freeze/thaw
    Do not freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not re-freeze aliquots.
    Packaging Information
    Transport Information
    Supplemental Information
    Specifications
    Global Trade Item Number
    Katalogové číslo GTIN
    574660 0

    Documentation

    Anti-Survivin Rabbit pAb MSDS

    Title

    Safety Data Sheet (SDS) 

    Anti-Survivin Rabbit pAb Certificates of Analysis

    TitleLot Number
    574660

    References

    Přehled odkazů
    Adida, C., et al. 1998. Am. J. Pathol.152, 43.
    Li, F., et al. 1998. Nature 396, 580.
    Lu, C.-D., et al. 1998. Cancer Res. 58, 1808.
    Ambrosini, G., et al. 1997. Nature Med. 3, 917.

    Brochure

    Title
    Caspases and other Apoptosis Related Tools Brochure
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision16-August-2007 RFH
    SynonymsAnti-Inhibitor of Apoptosis Protein, Anti-TIAP
    ApplicationELISA (1:10,000-1:100,000)
    Immunoblotting (1-10 µg/ml, chemiluminescence)
    Immunofluorescence (2-20 µg/ml)
    Immunohistochemistry (2-20 µg/ml)
    DescriptionImmunoaffinity purified rabbit polyclonal antibody. Recognizes the ~16 kDa survivin protein.
    BackgroundSurvivin is a member of the inhibitors of apoptosis proteins (IAPs), a widely expressed family of proteins that suppress apoptosis through direct caspase and pro-caspase inhibition. Similar to oncofetal antigens, survivin is highly expressed in less-differentiated embryonic cells or rapidly dividing tumor cells but not in fully differentiated adult tissues. Elevated levels of survivin are found in human fetal lung, liver, heart, kidney, and gastrointestinal tract and in most mouse embryonic tissues. High levels of survivin expression are also found in many common human cancers, including cancers of the lung, colon, pancreas, prostate, and breast. Expression of survivin correlates with the presence of both p53 and Bcl-2.
    HostRabbit
    Immunogen speciesHuman
    Immunogena synthetic peptide corresponding to amino acids near the C-terminus of human survivin
    IsotypeIgG
    Specieshuman, mouse
    FormLiquid
    FormulationIn PBS, 0.1% BSA.
    Concentration Label Please refer to vial label for lot-specific concentration
    Preservative≤0.1% sodium azide
    CommentsDoes not cross-react with EPR-1. Variables associated with assay conditions will dictate the optimal working dilution.
    Storage Avoid freeze/thaw
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not re-freeze aliquots.
    Toxicity Standard Handling
    ReferencesAdida, C., et al. 1998. Am. J. Pathol.152, 43.
    Li, F., et al. 1998. Nature 396, 580.
    Lu, C.-D., et al. 1998. Cancer Res. 58, 1808.
    Ambrosini, G., et al. 1997. Nature Med. 3, 917.