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AB3420-I Anti-Surfactant Protein A Antibody

Detect SP-A using this rabbit polyclonal antibody, Anti-Surfactant Protein A Antibody validated for use in western blotting & IHC (Paraffin).

Anti-Surfactant Protein A Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: SFTPA1, COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B UniProt Number: Q8IWL2
AB3420-I
100 µg  
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Speciální nabídky

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Speciální nabídky

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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IH(P)RbPurifiedPolyclonal Antibody
Description
Catalogue NumberAB3420-I
ReplacesAB3420
DescriptionAnti-Surfactant Protein A Antibody
Alternate Names
  • Pulmonary surfactant-associated protein A1
  • PSP-A
  • PSPA
  • SP-A
  • SP-A1
  • 35 kDa pulmonary surfactant-associated protein
  • Alveolar proteinosis protein
  • Collectin-4
Background InformationPulmonary surfactant-associated protein A1 (SP-A1, SFTPA1, PSP-A, SP-A) binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. There are four main surfactant proteins, known as SP-A, B, C, and D. SP-A was the first surfactant protein to be identified, and is also the most abundant. Its molecular mass varies from 26-38 kDa. It can be found in an open or closed form depending on the other substances present in the system. Calcium ions produce the closed-bouquet form. SP-A is necessary for the production of tubular myelin, a lipid transport structure unique to the lungs. Genetic variations in SP-A are a cause of susceptibility to pulmonary fibrosis idiopathic (IPF) and respiratory distress syndrome in premature infants (RDS).
References
Product Information
FormatPurified
Control
  • Human lung tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect SP-A using this rabbit polyclonal antibody, Anti-Surfactant Protein A Antibody validated for use in western blotting & IHC (Paraffin).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:200 dilution from a representative lot detected Surfactant Protein A in human lung tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-type lectin domain of human Surfactant Protein A.
EpitopeC-type lectin domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-type lectin domain of Surfactant Protein A.
Species Reactivity
  • Human
  • Mouse
Species Reactivity NoteDemonstrated to react with Human and Mouse. Predicted to react with Primate based on 100% sequence homology. Other homologies: Uniprot shows no homology to Rat.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • SFTPA1
  • COLEC4
  • PSAP
  • SFTP1
  • SFTPA
  • SFTPA1B
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~35 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human lung tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Surfactant Protein A in 10 µg of human lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
AB3420-I 04053252904585

Documentation

Anti-Surfactant Protein A Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Surfactant Protein A Antibody Certificates of Analysis

TitleLot Number
Anti-Surfactant Protein A - 2375590 2375590
Anti-Surfactant Protein A - 2455556 2455556
Anti-Surfactant Protein A - 2536487 2536487
Anti-Surfactant Protein A - 3176813 3176813
Anti-Surfactant Protein A - 3439711 3439711
Anti-Surfactant Protein A - 3520181 3520181
Anti-Surfactant Protein A - 3842852 3842852
Anti-Surfactant Protein A - 4083763 4083763
Anti-Surfactant Protein A - 4186079 4186079
Anti-Surfactant Protein A - Q2187159 Q2187159
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