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MABN501 Anti-SUR1 Antibody, clone N289/16

Anti-SUR1 Antibody, clone N289/16 is a highly specific mouse monoclonal antibody, that targets SUR & has been tested in western blotting & IHC.

Anti-SUR1 Antibody, clone N289/16 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Abcc8, Sur, Sur1 UniProt Number: Q09429
MABN501
100 µg  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN501
DescriptionAnti-SUR1 Antibody, clone N289/16
Alternate Names
  • ATP-binding cassette sub-family C member 8
  • Sulfonylurea receptor 1
Background InformationSulfonylurea receptor 1 (SUR1) is also called ATP-binding cassette sub-family C member 8, and is a member of the ABC transporter superfamily. SUR1 is a putative subunit of the beta-cell ATP-sensitive potassium channel (KATP) and functions as a regulator of ATP-sensitive K+ channels and insulin release.
References
Product Information
FormatPurified
Control
  • Mouse hypothalamus tissue lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-SUR1 Antibody, clone N289/16 is a highly specific mouse monoclonal antibody, that targets SUR & has been tested in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SUR1 in human thalamus tissue.
Biological Information
ImmunogenRecombinant protein corresponding to the C-terminus of rat SUR1.
EpitopeC-terminus
Cloneclone N289/16
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody recognizes the C-terminus of SUR1. Representative lot deteted Sur1 in crude brain membrane preparations
in SUR1 wild-type (WT) mouse cell lysate, and demonstrated a loss of signal in SUR1 knockout (KO) mouse cell lysate (Prof. J. Trimmer, University of California, Davis.).
IsotypeIgG1κ
Species Reactivity
  • Mouse
  • Rat
Species Reactivity NoteDemonstrated to react with Human and Mouse. Predicted to react with Rat based on immunogen design.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Abcc8
  • Sur
  • Sur1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 180 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse hypothalamus tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SUR1 in 10 µg of mouse hypothalamus tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABN501 04053252908163