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AB5871 Anti-SNAP-25 Antibody

Anti-SNAP-25 Antibody is an antibody against SNAP-25 for use in IP, WB, IH.

Anti-SNAP-25 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Synapse & Synaptic Biology Gene Symbol: SNAP25, SNAP, dJ1068F16.2, SNAP-25, FLJ23079, RIC-4, SUP, SEC9, RIC4, bA416N4.2 UniProt Number: P60880
AB5871
50 µL  
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Speciální nabídky

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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIP, WB, IHCGtPurifiedPolyclonal Antibody
Description
Catalogue NumberAB5871
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-SNAP-25 Antibody
Alternate Names
  • Synaptosomal-associated Protein 25
References
Product Information
FormatPurified
PresentationIgG fraction (protein A) in PBS with 50% Glycerol and 0.01% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-SNAP-25 Antibody is an antibody against SNAP-25 for use in IP, WB, IH.
Key Applications
  • Immunoprecipitation
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern blot: 1:100 - 1:2000
ELISA: 1:1000 - 1:100,000
Immunohistochemistry: 1:50 - 1:100

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenRecombinant human SNAP-25
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostGoat
SpecificitySNAP-25
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummarySynaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Gene Symbol
  • SNAP25
  • SNAP
  • dJ1068F16.2
  • SNAP-25
  • FLJ23079
  • RIC-4
  • SUP
  • SEC9
  • RIC4
  • bA416N4.2
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P60880 # t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
SIZE: 206 amino acids; 23315 Da
SUBUNIT: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with TRIM9, RIMS1, SNAP25BP and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1 (By similarity).
TISSUE SPECIFICITY: Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
PTM: Palmitoylated (By similarity).
SIMILARITY: SwissProt: P60880 ## Belongs to the SNAP-25 family. & Contains 2 t-SNARE coiled-coil homology domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
AB5871 04053252738821

Documentation

Anti-SNAP-25 Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-SNAP-25 Antibody Certificates of Analysis

TitleLot Number
GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2119726 2119726
GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2426496 2426496
GOAT ANTI-SNAP-25 - 2558365 2558365
GOAT ANTI-SNAP-25 - 3194683 3194683
GOAT ANTI-SNAP-25 - 3222657 3222657
GOAT ANTI-SNAP-25 - 3421945 3421945
GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY 2914550
GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY -
GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2092619 2092619
GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2108481 2108481
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Brochure

Title
Pathways and Biomarkers of Glutamatergic Synapse Flyer