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ABC1486 Anti-RIPK1 Antibody

ABC1486
100 μg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC1486
DescriptionAnti-RIPK1 Antibody
Alternate Names
  • Receptor-interacting serine/threonine-protein kinase 1
  • RIPK1
Background InformationReceptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-RIPK1 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of RIPK1.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis (IHC): 2.5 μg/mL from a representative lot detected RIPK1 in mouse kidney tissue.

Biological Information
ImmunogenRIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1.
EpitopeNear N-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Rat
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • RIPK1
  • RIP
  • RIP1
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~75 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat kidney tissue lysate.

Western Blotting Analysis (WB): 1 μg/mL of this antibody detected RIPK1 in rat kidney tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Global Trade Item Number
Katalogové číslo GTIN
ABC1486 04055977174632