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MAB3741 Anti-Protein Tyrosine Phosphatase µ Antibody, clone SBK15

This Anti-Protein Tyrosine Phosphatase μ Antibody, clone SBK15 is validated for use in IC, IP, WB for the detection of Protein Tyrosine Phosphatase μ.

Anti-Protein Tyrosine Phosphatase µ Antibody, clone SBK15 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Kinases & Phosphatases Gene Symbol: PTPRM, R-PTP-MU, RPTPU, RPTPM, PTPRL1, R-PTP-mu, hR-PTPu, MGC166994, EC 3.1.3.48 UniProt Number: P28827
MAB3741
100 µL  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
B, Ca, H, M, RICC, IP, WBMAscitesMonoclonal Antibody
Description
Catalogue NumberMAB3741
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Protein Tyrosine Phosphatase µ Antibody, clone SBK15
Alternate Names
  • Receptor-type Protein-tyrosine Phosphatase mu
  • R-PTP-MU
References
Product Information
FormatAscites
HS Code3002 15 90
PresentationAscites fluid.
Quality LevelMQ100
Applications
ApplicationThis Anti-Protein Tyrosine Phosphatase μ Antibody, clone SBK15 is validated for use in IC, IP, WB for the detection of Protein Tyrosine Phosphatase μ.
Key Applications
  • Immunocytochemistry
  • Immunoprecipitation
  • Western Blotting
Application NotesWestern blot (1:1,000)

Immunoprecipitation

Immunostaining (1:200)

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenCorresponds to amino acids 774-1452 of human PTPμ, purified from sf9 cells.
CloneSBK15
HostMouse
SpecificityRecognizes human PTPμ (Protein Tyrosine Phosphatase mu), a Receptor-type protein-tyrosine phosphatase. This antibody recognizes the cytoplasmic domain of PTPμ.
IsotypeIgG1
Species Reactivity
  • Bovine
  • Canine
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Gene Symbol
  • PTPRM
  • R-PTP-MU
  • RPTPU
  • RPTPM
  • PTPRL1
  • R-PTP-mu
  • hR-PTPu
  • MGC166994
  • EC 3.1.3.48
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P28827 # Involved in cell-cell adhesion through homophilic interactions. May play a key role in signal transduction and growth control.
SIZE: 1452 amino acids; 163633 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P28827 ## Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily. & Contains 4 fibronectin type-III domains. & Contains 1 Ig-like C2-type (immunoglobulin-like) domain. & Contains 1 MAM domain. & Contains 2 tyrosine-protein phosphatase domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MAB3741 04053252616150

Documentation

Anti-Protein Tyrosine Phosphatase µ Antibody, clone SBK15 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Protein Tyrosine Phosphatase µ Antibody, clone SBK15 Certificates of Analysis

TitleLot Number
MOUSE ANTI-PROTEIN TYROSINE PHOSPHATASE MU MONOCLONAL ANTIBODY - 2425929 2425929
MOUSE ANTI-PROTEIN TYROSINE PHOSPHATASE MU - 3509166 3509166
MOUSE ANTI-PROTEIN TYROSINE PHOSPHATASE MU -2579517 2579517

References

Reference overviewPub Med ID
Elevated glucocorticoid metabolism in placental tissue from first trimester pregnancies at increased risk of pre-eclampsia.
S Mukherjee,J L James,B Thilaganathan,G St J Whitley,A E Michael,J E Cartwright
Placenta  32  2010

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