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ABN278 Anti-Prospero homeobox protein 1/PROX1 Antibody

ABN278
100 µL  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN278
ReplacesAB5475
DescriptionAnti-Prospero homeobox protein 1/PROX1 Antibody
Alternate Names
  • Prospero homeobox protein 1
  • Homeobox prospero-like protein PROX1
  • PROX-1
Background InformationPROX1 (Prospero homeobox protein 1), the homolog of Drosophila Prospero, is a homeobox-containing transcription factor that binds and functions as a co-receptor of liver receptor homolog 1 (LRH1/NR5A2). It is a specific marker for lymphatic endothelial cells, as well as hepatoblasts and hepatocytes. Human Prox1 shares 97% amino acid sequence identity with mouse and rat Prox1.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Prospero homeobox protein 1/PROX1 Antibody is validated for use in western blotting & IHC for the detection of Prospero homeobox protein 1/PROX1.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Prospero homeobox protein 1/PROX1 in mouse E16 embryo thalamus tissues (Prof. Samual Pleasure, University of California, San Francisco.).

Alexa Fluor® is a registered trademark of Life Technologies, Inc.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human Prospero homeobox protein 1/PROX1.
EpitopeC-terminus
HostRabbit
Species Reactivity
  • Rat
  • Mouse
Species Reactivity NoteRat and Mouse. Predicted to react with Fish, Human, Chicken, and Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PROX1
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~95 kDa observed. Uniprot describes a molecular weight at 83 kDa. However, this protein may be observed between 80-110 kDa due to sumoylation and/or alternative start sites (Pan, M. R., et al. (2009). J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011). Genes Cells. 16(11):1063-1070.).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HEK293 nuclear extract.

Western Blotting Analysis: A 1:500 dilution of this antibody detected Prospero homeobox protein 1/PROX1 in 10 µg of HEK293 nuclear extract.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ABN278 04053252956720

Documentation

Anti-Prospero homeobox protein 1/PROX1 Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Prospero homeobox protein 1/PROX1 Antibody Certificates of Analysis

TitleLot Number
Anti-Prospero homeobox protein -2777849 2777849
Anti-Prospero homeobox protein 1/PROX1 - Q2383196 Q2383196
Anti-Prospero homeobox protein 1/PROX1 - 3271980 3271980
Anti-Prospero homeobox protein 1/PROX1 - 3385859 3385859
Anti-Prospero homeobox protein 1/PROX1 - 3613064 3613064
Anti-Prospero homeobox protein 1/PROX1 - 4042131 4042131
Anti-Prospero homeobox protein 1/PROX1 - 4188744 4188744
Anti-Prospero homeobox protein 1/PROX1 -2716140 2716140
Anti-Prospero homeobox protein 1/PROX1 Polyclonal Antibody 3140029
Anti-Prospero homeobox protein 1/PROX1 Polyclonal Antibody 2886338