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MABN1597 Anti-Olfactory Receptor 10G4 Antibody, clone 6C11.1

MABN1597
100 μg  
Purchase on Sigma-Aldrich

Speciální nabídky

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Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN1597
DescriptionAnti-Olfactory Receptor 10G4 Antibody, clone 6C11.1
Alternate Names
  • Olfactory receptor OR11-278
  • Olfactory Receptor 10G4
Background InformationOlfactory receptor 10G4 (UniProt Q8NGN3; also known as Olfactory receptor OR11-278) is encoded by the OR10G4 gene (Gene ID 390264) in human. Olfactory receptors belong to the class A rhodopsin-like family of G protein-coupled receptors (GPCRs). The human genome contains approximately 800 odorant receptor (OR) genes that have been shown to exhibit high genetic variability. Human has approximately 400 intact ORs, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. Odorant molecule binding induces an OR conformational change and interaction with the olfactory-type G protein, initiating downstream signaling that eventually results in an action potential from the depolarized OR neuron to the brain. Olfactory receptor 10G4 is a 311-amino acid protein with 4 extracellular domains (a.a. 1-23, 74-98, 160-196, 258-268), 7 transmembrane segments (a.a. 24-44, 53-73, 99-119, 139-159, 197-216, 237-257, 269-289), and 4 cytoplasmic regions (a.a. 45-52, 120-138, 217-236, 290-311).
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Olfactory Receptor 10G4 Antibody, clone 6C11.1 is an antibody against Olfactory Receptor 10G4 for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminal cytoplasmic tail of human Olfactory Receptor 10G4.
EpitopeC-terminal cytoplasmic tail.
Clone6C11.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • OR10G4
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~40 kDa observed. Target band size appears larger than the calculated molecular weight of 34.57 kDa due to glycosylation.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human olfactory tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Olfactory Receptor 10G4 in 10 µg of human olfactory tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABN1597 04055977329469