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MABN742 Anti-Neuroligin-1, clone 1C9.1 Antibody

This Anti-Neuroligin-1, clone 1C9.1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Neuroligin-1.

Anti-Neuroligin-1, clone 1C9.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience, Neuroscience Research Sub-Category: Synapse & Synaptic Biology, Growth Cones & Axon Guidance Gene Symbol: NLGN1, KIAA1070, NL1 UniProt Number: Q8N2Q7
MABN742
100 µg  
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Speciální nabídky

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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN742
DescriptionAnti-Neuroligin-1, clone 1C9.1 Antibody
Alternate Names
  • neuroligin 1
  • NLGN1
  • neuroligin-1
Background InformationNeuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Neuroligin-1, clone 1C9.1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Neuroligin-1.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroligin-1 in human cerebral cortex, rat cerebellum and rat cerebral cortex tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the extracellular domain of Human Neuroligin-1.
EpitopeExtracellular domain
Clone1C9.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2aκ
Species Reactivity
  • Rat
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • NLGN1
  • KIAA1070
  • NL1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~94 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroligin-1 in 10 µg of rat brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABN742 04053252996214

Documentation

Anti-Neuroligin-1, clone 1C9.1 Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Neuroligin-1, clone 1C9.1 Antibody Certificates of Analysis

TitleLot Number
Anti-Neuroligin-1, clone 1C9.1 - Q2454910 Q2454910
Anti-Neuroligin-1, clone 1C9.1 - 3476006 3476006
Anti-Neuroligin-1, clone 1C9.1 - 3887811 3887811
Anti-Neuroligin-1, clone 1C9.1 Monoclonal Antibody 2929159
Anti-Neuroligin-1, clone 1C9.1 Monoclonal Antibody 3079182

Brochure

Title
Pathways and Biomarkers of Glutamatergic Synapse Flyer