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ABT316 Anti-LTBP-3 Antibody

This Anti-LTBP-3 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of LTBP-3.

Anti-LTBP-3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: LTBP3 UniProt Number: Q9NS15
ABT316
100 µg  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT316
DescriptionAnti-LTBP-3 Antibody
Alternate Names
  • Latent-transforming growth factor beta-binding protein 3
  • LTBP-3
Background InformationLTBP3 is a critical secreted protein that is part of the multi-protein complex that controls the action and release of the powerful developmental, immune, and signaling factor TGF-beta. LTBP3’s specific role appears to be in regulating the activation of the TGFB1 precursor complex. The removal of LTBP3 is essential for the activation of the complex. LTBP3 is expressed in many tissues including heart, skeletal muscle, prostate, testis, small intestine, ovary, pancreas, and liver. Recent research also demonstrates that LTBP3 plays important roles in many human carcinomas including breast, hepatic, and mesothelioma.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-LTBP-3 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of LTBP-3.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: 2.0 µg/mL from a representative lot detected LTBP-3 in 10 µg of U2OS conditioned media.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected LTBP-3 in human prostate tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human LTBP-3.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • LTBP3
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~240 kDa observed. The calculated molecular weight of this protein is 139 kDa, but can be observed at ~240 kDa due to high glycosylation.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse testis tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected LTBP-3 in 10 µg of mouse testis tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ABT316 04055977039498