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MABF301 Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1

MABF301
100 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, FCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABF301
DescriptionAnti-Interleukin-7/IL-7 Antibody, clone 7B1.1
Alternate Names
  • Interleukin-7
  • IL-7
Background InformationThe protein named IL-7, or interleukin 7 is a hematopoietic growth factor secreted by stromal cell in the bone marrow and thymus but also produced by many other cell types including keratinocytes, epithelial cells, hepatocytes and macrophage/dendritic cells but not by classical lymphocytes. IL7 is a cytokine that has multiple functions and is critical for proper T cell maturation and lymphoid cell survival, and its expression stimulates the proliferation of B cells, T cell and NK cells. IL-7 is detected by cells via its receptor and binding results in a cascade of signals important for T cell development and for T cell survival within the periphery, as well as memory T cells. IL-7 expression is upregulated in various lymphomas and leukemias and because of its effects on T cell development IL-7 is being examined as a therapeutic agent for transplantation studies and even latent viral infection studies.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 is validated for use in western blotting & flow cytometry for the detection of Interleukin-7/IL-7.
Key Applications
  • Western Blotting
  • Flow Cytometry
Application NotesFlow Cytometry Analysis: 1 µg of this antibody detected recombinant Interleukin-7/IL-7 in Jurkat T and Raji B lymphocytes.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Interleukin-7/IL-7.
Clone7B1.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • IL7
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 17 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Interleukin 7 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected 0.5 µg of recombinant Interleukin-7/IL-7.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABF301 04053252943232

Documentation

Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 Certificates of Analysis

TitleLot Number
Anti-Interleukin-7/IL-7, clone 7B1.1 - Q2357785 Q2357785
Anti-Interleukin-7/IL-7, clone 7B1.1 - 3219738 3219738
Anti-Interleukin-7/IL-7, clone 7B1.1 - 3919687 3919687
Anti-Interleukin-7/IL-7, clone 7B1.1 - 4116916 4116916
Anti-Interleukin-7/IL-7, clone 7B1.1 -2645426 2645426
Anti-Interleukin-7/IL-7, clone 7B1.1 -2756662 2756662
Anti-Interleukin-7/IL-7, clone 7B1.1 -2757864 2757864
Anti-Interleukin-7/IL-7, clone 7B1.1 Monoclonal Antibody 2876030