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CBL251 Anti-Epithelial Specific Antigen Antibody, clone VU-1D9

CBL251
100 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICC, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberCBL251
DescriptionAnti-Epithelial Specific Antigen Antibody, clone VU-1D9
Alternate Names
  • Epithelial cell adhesion molecule
  • Ep-CAM
  • Adenocarcinoma-associated antigen
  • Cell surface glycoprotein Trop-1
  • Epithelial cell surface antigen
  • Epithelial glycoprotein
  • EGP
  • Epithelial glycoprotein 314
  • EGP314
  • hEGP314
  • KS 1/4 antigen
  • KSA
  • Major gastrointestinal tumor-associated protein GA733-2
  • Tumor-associated calcium signal transducer 1
  • CD326
Background InformationEpithelial specific antigen, also known as epithelial cell adhesion molecule (Ep-CAM) and epithelial glycoprotein (EGP), may act as an interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Epithelial specific antigen plays a role in embryonic stem cells proliferation and differentiation, and up-regulates the expression of FABP5, MYC, and cyclins A and E. Epithelial specific antigen is highly and selectively expressed by undifferentiated embryonic stem cells (ESCs). Protein levels rapidly diminish as soon as ESCs differentiate. Also expressed in most epithelial cell membranes and on the surface of adenocarcinoma.
References
Product Information
FormatPurified
HS Code3002 15 90
Control
  • MCF7 cell lyasate
PresentationPurified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Epithelial Specific Antigen Antibody, clone VU-1D9 is a highly specific mouse monoclonal antibody, that targets Epithelial Cell Marker & has been tested in western blotting, ICC & IHC.
Key Applications
  • Western Blotting
  • Immunocytochemistry
  • Immunohistochemistry
Application NotesImmunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Epithelial Specific Antigen in A431 cells.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Epithelial Specific Antigen in human prostate adenocarcinoma cells.
Biological Information
ImmunogenNCI-H69 whole cells
CloneVU-1D9
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • EPCAM
  • GA733-2
  • M1S2
  • M4S1
  • MIC18
  • TACSTD1
  • TROP1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~40 kDa observed. The calculated molecular weight of this protein is 35 kDa; however, this protein will run higher due to glycosylation.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in MCF7 cell lyate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Epithelial Specific Antigen in 10 µg of MCF7 cell lyate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
CBL251 04053252280955

Documentation

Anti-Epithelial Specific Antigen Antibody, clone VU-1D9 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Epithelial Specific Antigen Antibody, clone VU-1D9 Certificates of Analysis

TitleLot Number
Anti-Epithelial Specific Antigen, clone VU-1D9 - 2148197 2148197
Anti-Epithelial Specific Antigen, clone VU-1D9 - 2453167 2453167
Anti-Epithelial Specific Antigen, clone VU-1D9 - 3019805 3019805
Anti-Epithelial Specific Antigen, clone VU-1D9 - 3308873 3308873
Anti-Epithelial Specific Antigen, clone VU-1D9 - 3510210 3510210
Anti-Epithelial Specific Antigen, clone VU-1D9 - 3750046 3750046
Anti-Epithelial Specific Antigen, clone VU-1D9 - 3862663 3862663
Anti-Epithelial Specific Antigen, clone VU-1D9 - 3953631 3953631
Anti-Epithelial Specific Antigen, clone VU-1D9 - 4209939 4209939
Anti-Epithelial Specific Antigen, clone VU-1D9 -2585874 2585874