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217642 Anti-CD11b Mouse mAb (ICRF44)

Anti-CD11b Mouse mAb (ICRF44) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-αM Integrin, Anti-CR3, Anti-Mac-1

217642
  
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Přehled

Replacement Information

Tabulka spec. kláve

Host
M
Description
Overview

This product has been discontinued.





Recognizes the ~165 kDa αM integrin subunit. Also blocks homotypic neutrophil and fMLP-induced monocyte aggregation.
Catalogue Number217642
Brand Family Calbiochem®
SynonymsAnti-αM Integrin, Anti-CR3, Anti-Mac-1
References
ReferencesPetty, H.R., and Todd, R.F. 1993. J. Leukoc. Biol. 54, 492.
Myones, B.L., et al. 1988. J. Clin. Invest. 82, 640.
Malhotra, V., et al. 1986. Eur. J. Immunol. 16, 1117.
Product Information
FormLiquid
FormulationIn 150 mM NaCl, 100 mM potassium chloride, 50 mM sodium phosphate, pH 7.5.
Preservative≤0.1% sodium azide
Applications
Key Applications Cell Inhibition Assays
Flow Cytometry
Frozen Sections
Immunoprecipitation
Application NotesFlow Cytometry (5-20 µg/ml)
Frozen Sections (see comments)
Cell Inhibition Assays (see comments)
Immunoprecipitation (see comments)
Application CommentsMay be used to block homotypic neutrophil and monocyte (fLMP-induced) aggregation. This antibody has been reported to work for frozen sections and immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogenhuman monocytes DO NOT REACTIVATE. REMOVED FROM WEBSITE PER MAR/COM eCOMMERCE REQUEST. ALREADY DISCONTINUED. See PCS CBC-2015-6926. MJ 2-18-15
ImmunogenHuman
CloneICRF44
HostMouse
Purity≥95% by SDS-PAGE
IsotypeIgG₁
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
217642 0

Documentation

Anti-CD11b Mouse mAb (ICRF44) Certificates of Analysis

TitleLot Number
217642

References

Přehled odkazů
Petty, H.R., and Todd, R.F. 1993. J. Leukoc. Biol. 54, 492.
Myones, B.L., et al. 1988. J. Clin. Invest. 82, 640.
Malhotra, V., et al. 1986. Eur. J. Immunol. 16, 1117.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision25-July-2007 RFH
SynonymsAnti-αM Integrin, Anti-CR3, Anti-Mac-1
ApplicationFlow Cytometry (5-20 µg/ml)
Frozen Sections (see comments)
Cell Inhibition Assays (see comments)
Immunoprecipitation (see comments)
DescriptionProtein A purified mouse monoclonal antibody. Recognizes the ~165 kDa αM integrin subunit (CD11b).
BackgroundCD11b complexes with CD18 (β2 integrin) to form the complement receptor type 3 (CR3) heterodimer which binds ICAM, fibrinogen, C3b, and coagulation factor X. CD11b expression is restricted to leukocytes, mainly to myeloid and NK cells.
HostMouse
Immunogen speciesHuman
Immunogenhuman monocytes DO NOT REACTIVATE. REMOVED FROM WEBSITE PER MAR/COM eCOMMERCE REQUEST. ALREADY DISCONTINUED. See PCS CBC-2015-6926. MJ 2-18-15
CloneICRF44
IsotypeIgG₁
Specieshuman
FormLiquid
FormulationIn 150 mM NaCl, 100 mM potassium chloride, 50 mM sodium phosphate, pH 7.5.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE
Preservative≤0.1% sodium azide
CommentsMay be used to block homotypic neutrophil and monocyte (fLMP-induced) aggregation. This antibody has been reported to work for frozen sections and immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles.
Toxicity Standard Handling
ReferencesPetty, H.R., and Todd, R.F. 1993. J. Leukoc. Biol. 54, 492.
Myones, B.L., et al. 1988. J. Clin. Invest. 82, 640.
Malhotra, V., et al. 1986. Eur. J. Immunol. 16, 1117.