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ABN476 Anti-ACVR1C Antibody

ABN476
100 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN476
DescriptionAnti-ACVR1C Antibody
Alternate Names
  • Activin receptor type-1C
  • Activin receptor type IC
  • ACTR-IC
  • Activin receptor-like kinase 7
  • ALK-7
  • ACVR1C
Background InformationActivin receptor type-1 (ACVR1C) is a dimeric growth and differentiation factor belonging to the TKL Ser/Thr protein kinase family. Activins signal through a heteromeric complex of receptor serine kinases which include at least two, type I and two type II receptors. ACVR1C plays an important role in cell differentiation, growth arrest, and apoptosis. It is found in pancreas, heart, colon, small intestine, ovary, hippocampus, medulla oblongata, and putamen of the brain.
References
Product Information
FormatAffinity Purified
Control
  • Human placenta tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Activin receptor type-1 using this rabbit polyclonal antibody, Anti-ACVR1C Antibody validated for use in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human ACVR1C.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • ACVR1C
  • ALK7
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~62 kDa observed. Uniprot describes 4 isoforms at ~37 kDa, ~46 kDa, ~50 kDa, and ~55 kDa. Uncharacterized bands may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human placenta tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected ACVR1C in 15 µg of human placenta tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ABN476 04053252870439