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327768 Angiostatin, Human, Recombinant, Pichia pastoris

Angiostatin, Human, Recombinant, Pichia pastoris MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
327768
  
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Přehled

Replacement Information
Description
Overview

This product has been discontinued.

We apologize for the inconvenience, but we do not currently have an alternative product.






Recombinant, human angiostatin expressed in Pichia pastoris. Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1-4. A specific inhibitor of endothelial cell proliferation and one of the most potent and specific natural inhibitors of angiogenesis and metastatic tumor growth.
Catalogue Number327768
Brand Family Calbiochem®
References
ReferencesCao, Y. 1999. Haematologica 84, 643. Sim, B.K., et al. 1997. Cancer Res. 57, 1329. Wu, Z., et al. 1997. Biochem. Biophys. Res. Commun. 236, 651. Cao, Y., et al. 1996. J. Biol. Chem. 271, 29461. O'Reilly, M.S., et al. 1994. Cell 79, 315.
Product Information
CAS number86090-08-6
DeclarationSold under license of U.S. Patents 6,521,439, 6,723,536, and corresponding patents.
FormLiquid
FormulationIn 0.9% NaCl.
Applications
Biological Information
Biological activity10 µg/ml angiostatin will inhibit 60% tube formation in the presence of 10 ng/ml VEGF and 50% tube formation in the presence of 5 ng/ml bFGF.
Purity≥90% by HPLC
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
ContaminantsEndotoxin: ≤ 0.50 EU/mg
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
327768 0

Documentation

Angiostatin, Human, Recombinant, Pichia pastoris Certificates of Analysis

TitleLot Number
327768

References

Přehled odkazů
Cao, Y. 1999. Haematologica 84, 643. Sim, B.K., et al. 1997. Cancer Res. 57, 1329. Wu, Z., et al. 1997. Biochem. Biophys. Res. Commun. 236, 651. Cao, Y., et al. 1996. J. Biol. Chem. 271, 29461. O'Reilly, M.S., et al. 1994. Cell 79, 315.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-October-2007 JSW
DescriptionRecombinant, human angiostatin expressed in Pichia pastoris. Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1-4. A specific inhibitor of endothelial cell proliferation and one of the most potent and specific natural inhibitors of angiogenesis and metastatic tumor growth.
FormLiquid
FormulationIn 0.9% NaCl.
Concentration Label Please refer to vial label for lot-specific concentration
CAS number86090-08-6
Purity≥90% by HPLC
ContaminantsEndotoxin: ≤ 0.50 EU/mg
Biological activity10 µg/ml angiostatin will inhibit 60% tube formation in the presence of 10 ng/ml VEGF and 50% tube formation in the presence of 5 ng/ml bFGF.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesCao, Y. 1999. Haematologica 84, 643. Sim, B.K., et al. 1997. Cancer Res. 57, 1329. Wu, Z., et al. 1997. Biochem. Biophys. Res. Commun. 236, 651. Cao, Y., et al. 1996. J. Biol. Chem. 271, 29461. O'Reilly, M.S., et al. 1994. Cell 79, 315.