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658390 AG 9 - CAS 2826-26-8 - Calbiochem

AG 9 - CAS 2826-26-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: [(4-Methoxybenzylidene)malononitrile, α-Cyano-(4-methoxy)cinnamonitrile], Tyrphostin A1

Primary Target: negative control for inhibition of EGFR
658390
  
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
2826-26-8C₁₁H₈N₂O
Description
Overview

This product has been discontinued.



An inactive compound that can be used as a negative control for inhibition of EGFR (IC50 >1250 µM for EGFR kinase). Has been shown to inhibit IL-2 stimulated Tyk-2 phosphorylation in ConA-activated T cells.
Catalogue Number658390
Brand Family Calbiochem®
Synonyms[(4-Methoxybenzylidene)malononitrile, α-Cyano-(4-methoxy)cinnamonitrile], Tyrphostin A1
References
ReferencesBright, J.J., et al. 1999. J. Immunol. 162, 6255.
Gazit, A., et al. 1989. J. Med. Chem. 32, 2344.
Ruetten, H. and Thiemermann, C. 1997. Br. J. Pharmacol. 122, 59.
Product Information
CAS number2826-26-8
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₁H₈N₂O
Chemical formulaC₁₁H₈N₂O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetnegative control for inhibition of EGFR
Primary Target IC<sub>50</sub>>1250 µM for EGFR kinase
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
658390 0

Documentation

AG 9 - CAS 2826-26-8 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

AG 9 - CAS 2826-26-8 - Calbiochem Certificates of Analysis

TitleLot Number
658390

References

Přehled odkazů
Bright, J.J., et al. 1999. J. Immunol. 162, 6255.
Gazit, A., et al. 1989. J. Med. Chem. 32, 2344.
Ruetten, H. and Thiemermann, C. 1997. Br. J. Pharmacol. 122, 59.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-September-2008 RFH
Synonyms[(4-Methoxybenzylidene)malononitrile, α-Cyano-(4-methoxy)cinnamonitrile], Tyrphostin A1
DescriptionInactive inhibitor that can be used as a negative control for inhibition of EGFR (IC50 >1250 µM for EGFR kinase). Has been shown to inhibit IL-2 stimulated Tyk-2 phosphorylation in ConA-activated T cells.
FormYellow solid
CAS number2826-26-8
Chemical formulaC₁₁H₈N₂O
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityAcetic acid, DMSO, or ethanol (10 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesBright, J.J., et al. 1999. J. Immunol. 162, 6255.
Gazit, A., et al. 1989. J. Med. Chem. 32, 2344.
Ruetten, H. and Thiemermann, C. 1997. Br. J. Pharmacol. 122, 59.