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SCC711 3dGRO™ Pancreatic Organoids (PPTO.76)

Cryopreserved patient derived pancreatic cancer organoids (PDOs)

SCC711
≥ 1500 organoids/vial  
Purchase on Sigma-Aldrich

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Replacement Information
Description
Catalogue NumberSCC711
Description3dGRO™ Pancreatic Organoids (PPTO.76)
OverviewThe pancreas is both an endocrine and exocrine organ that plays role in digestion and metabolic homeostasis. Endocrine compartments include the alpha and beta cells which secrete the hormones glucagon and insulin and exocrine compartment including acinar cells, which store and secrete digestive enzymes and highly branched, tubular epithelial tree–like ductal networks. Pancreatic ductal adenocarcinoma (PDACs) is one of the most lethal forms of cancer with 5-year survival rates less than 8% and is projected to be the second most common cause of cancer-related deaths by 2030.

Recent breakthroughs in three-dimensional (3D) culture methods have led to the development of organoid culture platforms, which allow researchers to perform translational research on long-term in vitro cultures not limited by barriers present in 2D culture or animal models. We now offer a comprehensive collection of patient derived pancreatic ductal adenocarcinoma cancer (PDAC) organoids for cancer research and drug discovery applications.

Cell Line Characteristics
• Sex: Female
• Age: 57 Years
• Organ: Pancreas (Primary Tumor)
• Disease: Ductal Adenocarcinoma (KRAS mutation: G12D)
Alternate Names
  • Pancreatic Cancer Organoid
  • PDAC Organoid
  • Pancreatic Tumor Organoid
  • Pancreatic Ductal Organoid
References
Product Information
Components
  • 1 vial of ≥ 1500 organoids
Quality LevelMQ100
Applications
ApplicationCryopreserved patient derived pancreatic cancer organoids (PDOs)
Key Applications
  • Stem Cell Culture
  • Cell Culture
Application Notes3dGRO™ is a trademark of KGaA, Darmstadt, Germany.
3dGRO™ organoids were derived utilizing HUB Organoid Technology.
The purchaser of this product shall agree to HUB’s terms of use, which shall be separately acknowledged and accepted by such purchaser, prior to transfer of this product to purchaser.
Biological Information
HostHuman
Cell Line Type
  • Cancer Cells
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance• Viability: ≥1500 viable organoids/vial
• Organoid Growth: Pass
• Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Mycoplasma Contamination: Negative
• STR Profile: Pass
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore in liquid nitrogen. The organoids can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
Packaging Information
Material Size≥ 1500 organoids/vial
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
SCC711 04065269132301