324880 Sigma-Aldrich(–)-Epigallocatechin Gallate - CAS 989-51-5 - Calbiochem
One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties.
More>> One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties. Less<<Synonyms: EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol-3-(3,4,5-trihydroxybenzoate), DNA Methyltransferase Inhibitor IV, HAT Inhibitor X, Histone Acetyltransferase Inhibitor X, p300/CBP Inhibitor VIII, PCAF Inhibitor V, DNA MTase Inhibitor IV
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Přehled
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Tabulka spec. kláve
CAS # | Empirical Formula |
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989-51-5 | C₂₂H₁₈O₁₁ |
Products
Katalogové číslo | Balení | ks/bal. | |
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324880-10MG | Plastová ampulka | 10 mg |
Product Information | |
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CAS number | 989-51-5 |
ATP Competitive | N |
Form | Faint pink solid |
Hill Formula | C₂₂H₁₈O₁₁ |
Chemical formula | C₂₂H₁₈O₁₁ |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | PMA-induced skin thickening |
Primary Target IC<sub>50</sub> | 210-470 nM against Dnmt1; 30, 50, 60 and 70 µM for p300, CBP, PCAF and TIP60 |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | N |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS | |
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RTECS | KB5200000 |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Katalogové číslo | GTIN |
324880-10MG | 04055977196092 |
Documentation
(–)-Epigallocatechin Gallate - CAS 989-51-5 - Calbiochem MSDS
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(–)-Epigallocatechin Gallate - CAS 989-51-5 - Calbiochem Certificates of Analysis
Title | Lot Number |
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324880 |
References
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Choi, K.C., et al. 2009. Cancer Res. 69, 583. Dell'Aicia, I., et al. 2004. EMBO reports 5, 1. Tachibana, H., et al. 2004. Nat. Struct. Mol. Biol. 11, 380. Naasami, I., et al. 1998. Biochem. Biophys. Res. Commun. 249, 391. Ahmad, N., et al. 1997. J. Natl. Cancer 89, 1881. Chan, M.M.-Y., et al. 1997. Biochem. Pharmacol. 54, 1281. Lin, Y.-L., and Lin, J.-K. 1997. Mol. Pharmacol. 52, 465. Fiala, E.S., et al. 1996. Experientia 52, 922. Katiyar, S.K., et al. 1995. J. Invest. Dermatol. 105, 394. Liao, S., et al. 1995. Cancer Lett. 96, 239. Yamane, T., et al. 1995. Cancer Res. 55, 2081. Huang, M.T., et al. 1992. Carcinogenesis 13, 947. |
Brochure
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Caspases and other Apoptosis Related Tools Brochure |