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106447 tri-Sodium citrate dihydrate

EMPROVE® EXPERT Ph Eur,BP,ChP,JP,USP,ACS,E 331

tri-Sodium citrate dihydrate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trisodium Citrate, Sodium Citrate, Dihydrate

CAS #: 6132-04-3 EC Number: 200-675-3 Molar Mass: 294.10 g/mol Hill Formula: C₆H₅Na₃O₇ * 2 H₂O Grade: Ph Eur,BP,ChP,JP,USP,ACS,E 331
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106447
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Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
6132-04-3200-675-3C₆H₅Na₃O₇ * 2 H₂O294.10 g/molPh Eur,BP,ChP,JP,USP,ACS,E 331

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          1.06447.9029
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              1.06447.9051
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                  Description
                  Catalogue Number106447
                  SynonymsTrisodium Citrate, Sodium Citrate, Dihydrate
                  References
                  Product Information
                  CAS number6132-04-3
                  EC number200-675-3
                  GradePh Eur,BP,ChP,JP,USP,ACS,E 331
                  Hill FormulaC₆H₅Na₃O₇ * 2 H₂O
                  Molar Mass294.10 g/mol
                  HS Code2918 15 00
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ500
                  Applications
                  Biological Information
                  Physicochemical Information
                  Melting Point300 °C (anhydrous substance)
                  pH value7.5 - 9.0 (50 g/l, H₂O, 25 °C)
                  Bulk density600 kg/m3
                  Solubility720 g/l
                  Dimensions
                  Materials Information
                  Toxicological Information
                  LD 50 oralLD50 Rat > 8000 mg/kg
                  Safety Information according to GHS
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 1 slightly hazardous to water
                  Disposal3
                  Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageStore at +2°C to +30°C.
                  Packaging Information
                  Transport Information
                  Declaration (railroad and road) ADR, RIDKein Gefahrgut
                  Declaration (transport by air) IATA-DGRNo Dangerous Good
                  Declaration (transport by sea) IMDG-CodeNo Dangerous Good
                  Supplemental Information
                  Specifications
                  Assay (perchloric acid titration, calculated on dried substance)99.0 - 100.5 %
                  Assay (perchloric acid titration)≥ 99.0 %
                  Identitypasses test
                  Appearance of solutionpasses test
                  Alkalinitypasses test
                  Acidity or alkalinitypasses test
                  pH-value (5 %; water)7.5 - 8.5
                  pH-value (5 %; water; 25 °C)7.0 - 9.0
                  Insoluble matter≤ 0.005 %
                  Chloride (Cl)≤ 0.003 %
                  Sulfate (SO₄)≤ 0.005 %
                  As (Arsenic)≤ 0.0001 %
                  Ba (Barium)≤ 0.003 %
                  Ca (Calcium)≤ 0.005 %
                  Fe (Iron)≤ 0.0005 %
                  Hg (Mercury)≤ 0.0001 %
                  NH₃ (Ammonia)≤ 0.003 %
                  Pb (Lead)≤ 0.0001 %
                  Calcium salts or oxalate≤ 0.005 %
                  Heavy metals (ACS)≤ 0.0005 %
                  Heavy metals (as Pb)≤ 0.0005 %
                  Oxalate (C₂O₄)≤ 0.01 %
                  Tartrate (as C₄H₄O₆)passes test
                  Residual solvents (ICH Q3C)excluded by manufacturing process
                  Readily carbonisable substancepasses test
                  Loss on drying (180 °C)11.0 - 13.0 %
                  Water11.0 - 13.0 %
                  Total aerobic microbial count≤ 100 CFU/g
                  Total yeast and mould count≤ 10 CFU/g
                  Salmonella species (absent in 10 g)passes test
                  E.coli (absent in 1 g)passes test
                  Staphylococcus aureus (absent in 1 g)passes test
                  Pseudomonas aeruginosa (absent in 1 g)passes test
                  Bile tolerante gram negative bacteria (absent in 1g)passes test
                  Candida albicans (absent in 1 g)passes test
                  Endotoxins≤ 2.5 I.U./g
                  DNases (Exo- and endonucleases) (not detectable)passes test
                  RNases (not detectable)passes test
                  Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                  Corresponds to Ph Eur,BP,ChP,JP,USP,ACS,E 331
                  Conforms to the purity criteria on food additives according to the current European Commission Regulation.
                  Global Trade Item Number
                  Catalogue Number GTIN
                  1.06447.1000 04022536076928
                  1.06447.5000 04022536076942
                  1.06447.9029 04022536940328
                  1.06447.9051 04065272192576

                  Documentation

                  Material Qualification Dossier

                  TitleVersion
                  8.0

                  Quality Management Dossier (Open Access)

                  Title

                  Operational Excellence Dossier

                  Title

                  tri-Sodium citrate dihydrate SDS

                  Title

                  Safety Data Sheet (SDS) 

                  tri-Sodium citrate dihydrate Certificates of Analysis

                  Product Number PackagingSpecificationLot Number
                  1.06447.1000 Plastic bottlePDF Specification Document
                  1.06447.5000 Plastic bottlePDF Specification Document
                  1.06447.9029 Double PE SackPDF Specification Document
                  1.06447.9051 Plastic drumPDF Specification Document

                  Certificates

                  Title