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14-764 Tie2 (Y897S) Protein, active, 10 µg

Active, N-terminal 6His-tagged recombinant human Tie2 residues 771-end. For use in Kinase Assays.

14-764
10 µg  Also available in 250μg size-call for pricing and availability and reference catalog number 14-764M when ordering the 250μg size.
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      Overview

      Replacement Information
      Description
      Catalogue Number14-764
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionTie2 (Y897S) Protein, active, 10 µg
      OverviewN-terminal 6His-tagged recombinant human Tie2 residues 771-end.
      Background InformationThe Y897S substitution is a gain-of-function mutation associated with hereditary venous malformations (Calvert et al., (1999), Hum. Mol. Genet. 8, 1279-1289).
      References
      Product Information
      Presentation50mM Tris/HCl pH8.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij 35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal 6His-tagged recombinant human Tie2 residues 771-end. For use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed by baculovirus in Sf21 insect cell.
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • TEK
      • TIE2
      Protein TargetTie2
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyTK
      UniProt Number
      Molecular Weight42kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore -70°C. For maximum recovery of product, centrifuge original vial prior to removing the cap.
      Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
      Packaging Information
      Material Size10 µg
      Material PackageAlso available in 250μg size-call for pricing and availability and reference catalog number 14-764M when ordering the 250μg size.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-764 04053252676611

      Documentation