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605195 Thrombin, Human Plasma, High Activity

Thrombin, Human Plasma, High Activity MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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605195
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Overview

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605195-1000UCN
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      605195-100UCN
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          605195-5000UCN
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              Description
              OverviewDesigned for use in thrombin clotting time tests. Key enzyme that activates factor XIII and converts fibrinogen into fibrin.
              Catalogue Number605195
              Brand Family Calbiochem®
              References
              ReferencesForsberg, G., et al. 1992. J. Protein Chem. 11, 201.
              Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
              Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
              Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.
              Product Information
              CAS number9002-04-4
              Unit of DefinitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
              FormLyophilized solid
              FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
              Quality LevelMQ100
              Applications
              Biological Information
              PurityComplete activation from homogeneous prothrombin by SDS-PAGE
              SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
              Specific Activity≥2800 NIH units/mg protein
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSXO8950000
              Safety Information
              R PhraseR: 20/21/22

              Harmful by inhalation, in contact with skin and if swallowed.
              S PhraseS: 36

              Wear suitable protective clothing.
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Blue Ice Only
              Toxicity Harmful
              Storage -20°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              Catalogue Number GTIN
              605195-1000UCN 04055977188417
              605195-100UCN 04055977188400
              605195-5000UCN 04055977188424

              Documentation

              Thrombin, Human Plasma, High Activity SDS

              Title

              Safety Data Sheet (SDS) 

              Thrombin, Human Plasma, High Activity Certificates of Analysis

              TitleLot Number
              605195

              References

              Reference overview
              Forsberg, G., et al. 1992. J. Protein Chem. 11, 201.
              Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
              Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
              Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision19-May-2008 RFH
              DescriptionDesigned for use in thrombin clotting time tests. Serine protease formed in the plasma during the clotting process from prothrombin, calcium, and thromboplasmin. Acts on the soluble plasma protein fibrinogen to convert it to an insoluble fibrin clot. Prepared from homogenous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. Designed for use in thrombin time tests.
              FormLyophilized solid
              FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
              SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
              CAS number9002-04-4
              RTECSXO8950000
              PurityComplete activation from homogeneous prothrombin by SDS-PAGE
              Specific activity≥2800 NIH units/mg protein
              Unit definitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
              SolubilityH₂O (1 mg/ml). Solution will have a cloudy appearance.
              Storage -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
              Toxicity Harmful
              Merck USA index14, 9383
              ReferencesForsberg, G., et al. 1992. J. Protein Chem. 11, 201.
              Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
              Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
              Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.

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              Categories

              Life Science Research > Proteins and Enzymes > Other Enzymes