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506188 Sertraline Hydrochloride - CAS 79559-97-0 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Serotonin (5-HT) Reuptake Inhibitor, Sertraline, Zoloft

Primary Target: 5-HT uptake transporter
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506188
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
79559-97-0C₁₇H₁₇Cl₂N•HCl

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      Description
      OverviewA very potent uptake inhibitor highly selective for serotonin (Ki = 3.3 nM). Clinically prescribed as an antidepressant drug. Often used in studying major depressive disorders.
      Catalogue Number506188
      Brand Family Calbiochem®
      SynonymsSerotonin (5-HT) Reuptake Inhibitor, Sertraline, Zoloft
      References
      ReferencesBrunoni, R., et al. 2013. JAMA Psychiatry. 70, 383.
      Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol. 40, 481.
      Heym, J., et al. 1988. J. Clin. Psychiatry. 49 Suppl, 40.
      Koe, K., et al. 1983. J. Pharmacol. Exp. Ther. 226, 700.
      Product Information
      CAS number79559-97-0
      FormWhite solid
      Hill FormulaC₁₇H₁₇Cl₂N•HCl
      Chemical formulaC₁₇H₁₇Cl₂N•HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target5-HT uptake transporter
      Primary Target K<sub>i</sub>3.3 nM
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.06188.0001CN 04055977243147

      Documentation

      Sertraline Hydrochloride - CAS 79559-97-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Brunoni, R., et al. 2013. JAMA Psychiatry. 70, 383.
      Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol. 40, 481.
      Heym, J., et al. 1988. J. Clin. Psychiatry. 49 Suppl, 40.
      Koe, K., et al. 1983. J. Pharmacol. Exp. Ther. 226, 700.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-November-2013 JSW
      SynonymsSerotonin (5-HT) Reuptake Inhibitor, Sertraline, Zoloft
      DescriptionA very potent uptake inhibitor highly selective for serotonin (Ki = 3.3 nM). Clinically prescribed as an antidepressant drug. Often used in studying major depressive disorders.
      FormWhite solid
      CAS number79559-97-0
      Chemical formulaC₁₇H₁₇Cl₂N•HCl
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (100 mM) or Ethanol (50 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBrunoni, R., et al. 2013. JAMA Psychiatry. 70, 383.
      Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol. 40, 481.
      Heym, J., et al. 1988. J. Clin. Psychiatry. 49 Suppl, 40.
      Koe, K., et al. 1983. J. Pharmacol. Exp. Ther. 226, 700.