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508159 Salvinorin A - CAS 83729-01-5 - Calbiochem

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
83729-01-5C₂₃H₂₈O₈

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      Description
      OverviewA highly potent and selective non-alkaloid positive allosteric modulator of Κ-opioid receptors (Ki = 4.3 nM and 16 nM for native and cloned κ-opioid receptors, respectively). Also acts as a D2DR partial agonist (Ki = 5-10 nM). Used in studies of addition.
      Catalogue Number508159
      Brand Family Calbiochem®
      Synonymsκ-opioid Receptor Agonist, Salvinorin A, Divinorin A
      References
      ReferencesRoth, B. et al., 2002. PNAS. 99, 11934.
      Valdés III., j., et al., 1984. J. Organic Chem. 49, 4716.
      Ortega, A., et al., 1982. J. of Chem. Society, Perkins Transactions I. 2505.
      Product Information
      CAS number83729-01-5
      FormWhite solid
      Hill FormulaC₂₃H₂₈O₈
      Chemical formulaC₂₃H₂₈O₈
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetk opioid receptor
      Primary Target K<sub>i</sub>4.3 nM
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.08159.0001CN 04055977242911

      Documentation

      Salvinorin A - CAS 83729-01-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Salvinorin A - CAS 83729-01-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      508159

      References

      Reference overview
      Roth, B. et al., 2002. PNAS. 99, 11934.
      Valdés III., j., et al., 1984. J. Organic Chem. 49, 4716.
      Ortega, A., et al., 1982. J. of Chem. Society, Perkins Transactions I. 2505.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision31-October-2013 JSW
      Synonymsκ-opioid Receptor Agonist, Salvinorin A, Divinorin A
      DescriptionA highly potent and selective non-alkaloid positive allosteric modulator of Κ-opioid receptors (Ki = 4.3 nM and 16 nM for native and cloned κ-opioid receptors, respectively). Also acts as a D2DR partial agonist (Ki = 5-10 nM). Used in studies of addition.
      FormWhite solid
      CAS number83729-01-5
      Chemical formulaC₂₃H₂₈O₈
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (50 mM) or Ethanol (10 mM)
      Storage Protect from light
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesRoth, B. et al., 2002. PNAS. 99, 11934.
      Valdés III., j., et al., 1984. J. Organic Chem. 49, 4716.
      Ortega, A., et al., 1982. J. of Chem. Society, Perkins Transactions I. 2505.