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851009 PyBOP

Overview

Key Spec Table

CAS #Hill FormulaMolar Mass
128625-52-5C₁₈H₂₈N₆OP * F₆P520.39 g/mol

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              Description
              Catalogue Number851009
              Replaces01-62-0016
              Brand Family Novabiochem®
              Alternate Names
              • Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate
              Background InformationThe standard in situ coupling reagent for solid phase peptide synthesis [1-5]. This product can replace BOP in all applications without loss of performance. Unlike uronium-based reagents, PyBOP® does not give rise to guanidinated by-products during cyclization and fragment condensation reactions.

              The product number for this product was previously 01-62-0016.

              To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
              Product Information
              CAS number128625-52-5
              Hill FormulaC₁₈H₂₈N₆OP * F₆P
              Molar Mass520.39 g/mol
              HS Code2933 99 80
              Structure formula ImageStructure formula Image
              Quality LevelMQ400
              Applications
              ApplicationPyBOP Novabiochem®. CAS 128625-52-5, molar mass 520.39 g/mol.
              Physicochemical Information
              Density1.438 g/cm3 (20 °C)
              Melting Point140 - 155 °C
              Vapor pressure<1 hPa (25 °C)
              Safety Information according to GHS
              Hazard Pictogram(s) Hazard Pictogram(s)
              Hazard Pictogram(s)
              Hazard Statement(s)H302: Harmful if swallowed.
              H317: May cause an allergic skin reaction.
              H410: Very toxic to aquatic life with long lasting effects.
              Precautionary Statement(s)P261: Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
              P264: Wash skin thoroughly after handling.
              P273: Avoid release to the environment.
              P280: Wear protective gloves.
              P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
              P302 + P352: IF ON SKIN: Wash with plenty of water.
              Signal WordWarning
              Storage class10 - 13 Other liquids and solids
              WGKWGK 3 highly hazardous to water
              Safety Information
              Categories of dangerirritant
              Storage and Shipping Information
              StorageStore at +2°C to +8°C.
              Transport Information
              Declaration (railroad and road) ADR, RIDUN 3077 , 9, III
              Declaration (transport by air) IATA-DGRUN 3077 , 9, III
              Declaration (transport by sea) IMDG-CodeUN 3077 , 9, III, Marine Pollutant: P
              Specifications
              Color (visual)white to slight yellow to beige
              Appearance of substance (visual)powder
              Identity (IR)passes test
              Assay (HPLC, area%)≥ 99.0 % (a/a)
              Solubility (1 mmole in 2 ml DMF)clearly soluble
              Global Trade Item Number
              Catalogue Number GTIN
              8.51009.0025 04027269081089
              8.51009.0100 04027269081096
              8.51009.1000 04027269131296