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ProSep®-vA High Capacity Chromatography Media

ProSep®-vA chromatography media are designed to facilitate highly efficient, cost effective purification of monoclonal, polyclonal and engineered antibodies.

Overview

The ProSep®-vA family of protein A affinity media is designed to facilitate highly efficient, cost effective purification of monoclonal, polyclonal and engineered antibodies. These resins are manufactured using no mammalian derived products.

ProSep®-vA High Capacity consists of protein A immobilized on porous glass that is permeated by interconnecting pores of uniform and precisely controlled size. ProSep®-vA chromatography media exhibit chemical and mechanical stability over a range of conditions such as low pH, exposure to detergents, buffers of varying ionic strengths and many organic solvents.

Its matrix is optimized for large-scale production use and offers significant advantages compared with other available matrices:

  • Proven technology
  • Rigid and incompressible
  • High flow rates with low back pressure
  • No shrinkage or swelling
  • High throughput and productivity
  • Reliable scale up
  • Flexible operating conditions
  • Lower cost of operation

ProSep®--vA High Capacity Media

ProSep®-vA High Capacity media is suited as capture step in the purification of therapeutic antibodies. It was the first commercially available animal free protein A resin, designed for the large-scale purification of monoclonal, polyclonal and engineered antibodies.

ProSep®--vA High Capacity Specifications
Static binding capacity: ≥ 40 mg/mL